Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | AZD8055 | 2 | 72 | 0.0032 | 18499.0 | 18525.7 | 2822.7 | -2.49 | 0.999 | 0.999 | 2.714 | HCC1806 AZD8055 0 2 |
| HCC1806 | AZD8055 | 2 | 72 | 0.0032 | 18039.0 | 18525.7 | 2822.7 | -2.49 | 0.980 | 0.974 | 2.714 | HCC1806 AZD8055 0 2 |
| HCC1806 | AZD8055 | 2 | 72 | 0.0032 | 18863.0 | 18525.7 | 2822.7 | -2.49 | 1.010 | 1.020 | 2.714 | HCC1806 AZD8055 0 2 |
| HCC1806 | AZD8055 | 2 | 72 | 0.01 | 16856.0 | 18525.7 | 2822.7 | -2.0 | 0.932 | 0.910 | 2.714 | HCC1806 AZD8055 0 2 |
| HCC1806 | AZD8055 | 2 | 72 | 0.0316 | 15946.0 | 18525.7 | 2822.7 | -1.5 | 0.893 | 0.861 | 2.714 | HCC1806 AZD8055 0 2 |
| HCC1806 | AZD8055 | 2 | 72 | 0.0316 | 15293.0 | 18525.7 | 2822.7 | -1.5 | 0.864 | 0.826 | 2.714 | HCC1806 AZD8055 0 2 |
| HCC1806 | AZD8055 | 2 | 72 | 0.0316 | 15357.0 | 18525.7 | 2822.7 | -1.5 | 0.866 | 0.829 | 2.714 | HCC1806 AZD8055 0 2 |
| HCC1806 | AZD8055 | 2 | 72 | 0.1 | 12537.0 | 18525.7 | 2822.7 | -1.0 | 0.732 | 0.677 | 2.714 | HCC1806 AZD8055 0 2 |
| HCC1806 | AZD8055 | 2 | 72 | 0.1 | 11490.0 | 18525.7 | 2822.7 | -1.0 | 0.677 | 0.620 | 2.714 | HCC1806 AZD8055 0 2 |
| HCC1806 | AZD8055 | 2 | 72 | 0.3162 | 9550.0 | 18525.7 | 2822.7 | -0.5 | 0.567 | 0.516 | 2.714 | HCC1806 AZD8055 0 2 |
| HCC1806 | AZD8055 | 2 | 72 | 0.3162 | 8751.0 | 18525.7 | 2822.7 | -0.5 | 0.517 | 0.472 | 2.714 | HCC1806 AZD8055 0 2 |
| HCC1806 | AZD8055 | 2 | 72 | 3.1623 | 7972.0 | 18525.7 | 2822.7 | 0.5 | 0.466 | 0.430 | 2.714 | HCC1806 AZD8055 0 2 |
| HCC1806 | AZD8055 | 2 | 72 | 3.1623 | 7967.0 | 18525.7 | 2822.7 | 0.5 | 0.466 | 0.430 | 2.714 | HCC1806 AZD8055 0 2 |
| HCC1806 | AZD8055 | 2 | 72 | 3.1623 | 7955.0 | 18525.7 | 2822.7 | 0.5 | 0.465 | 0.429 | 2.714 | HCC1806 AZD8055 0 2 |
| HCC1806 | AZD8055 | 2 | 72 | 10.0 | 7623.0 | 18525.7 | 2822.7 | 1.0 | 0.442 | 0.411 | 2.714 | HCC1806 AZD8055 0 2 |
| HCC1806 | AZD8055 | 2 | 72 | 10.0 | 7347.0 | 18525.7 | 2822.7 | 1.0 | 0.423 | 0.397 | 2.714 | HCC1806 AZD8055 0 2 |
| HCC1806 | AZD8055 | 3 | 72 | 0.001 | 14117.0 | 14413.7 | 2222.1 | -3.0 | 0.985 | 0.979 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.001 | 14547.0 | 14413.7 | 2222.1 | -3.0 | 1.010 | 1.010 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.001 | 14500.0 | 14413.7 | 2222.1 | -3.0 | 1.000 | 1.010 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.0032 | 14009.0 | 14413.7 | 2222.1 | -2.49 | 0.979 | 0.972 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.01 | 13559.0 | 14413.7 | 2222.1 | -2.0 | 0.955 | 0.941 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.01 | 13818.0 | 14413.7 | 2222.1 | -2.0 | 0.969 | 0.959 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.01 | 13170.0 | 14413.7 | 2222.1 | -2.0 | 0.934 | 0.914 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.0316 | 13418.0 | 14413.7 | 2222.1 | -1.5 | 0.948 | 0.931 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.01 | 14847.0 | 14413.7 | 2222.1 | -2.0 | 1.020 | 1.030 | 2.697 | HCC1806 QL-V-107 0 3 |