Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-V-107 | 2 | 72 | 0.01 | 18451.0 | 18525.7 | 2822.7 | -2.0 | 0.997 | 0.996 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 0.0316 | 17594.0 | 18525.7 | 2822.7 | -1.5 | 0.962 | 0.950 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 0.0316 | 17934.0 | 18525.7 | 2822.7 | -1.5 | 0.976 | 0.968 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 0.0316 | 17828.0 | 18525.7 | 2822.7 | -1.5 | 0.972 | 0.962 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | AZD8055 | 1 | 72 | 0.001 | 16973.0 | 17793.8 | 2895.7 | -3.0 | 0.964 | 0.954 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.001 | 16989.0 | 17793.8 | 2895.7 | -3.0 | 0.965 | 0.955 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.001 | 17216.0 | 17793.8 | 2895.7 | -3.0 | 0.975 | 0.968 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.0032 | 16634.0 | 17793.8 | 2895.7 | -2.49 | 0.949 | 0.935 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.0032 | 18684.0 | 17793.8 | 2895.7 | -2.49 | 1.040 | 1.050 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.01 | 15910.0 | 17793.8 | 2895.7 | -2.0 | 0.916 | 0.894 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.01 | 16231.0 | 17793.8 | 2895.7 | -2.0 | 0.931 | 0.912 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.01 | 15833.0 | 17793.8 | 2895.7 | -2.0 | 0.913 | 0.890 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.0316 | 14443.0 | 17793.8 | 2895.7 | -1.5 | 0.847 | 0.812 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.1 | 11557.0 | 17793.8 | 2895.7 | -1.0 | 0.696 | 0.649 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.1 | 10549.0 | 17793.8 | 2895.7 | -1.0 | 0.638 | 0.593 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.1 | 11288.0 | 17793.8 | 2895.7 | -1.0 | 0.681 | 0.634 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.3162 | 8697.0 | 17793.8 | 2895.7 | -0.5 | 0.522 | 0.489 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.3162 | 8542.0 | 17793.8 | 2895.7 | -0.5 | 0.511 | 0.480 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 1.0 | 7466.0 | 17793.8 | 2895.7 | 0.0 | 0.436 | 0.420 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 1.0 | 7271.0 | 17793.8 | 2895.7 | 0.0 | 0.421 | 0.409 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 3.1623 | 7396.0 | 17793.8 | 2895.7 | 0.5 | 0.430 | 0.416 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 10.0 | 6394.0 | 17793.8 | 2895.7 | 1.0 | 0.353 | 0.359 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 10.0 | 7210.0 | 17793.8 | 2895.7 | 1.0 | 0.417 | 0.405 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | QL-V-107 | 2 | 72 | 0.3162 | 11225.0 | 18525.7 | 2822.7 | -0.5 | 0.663 | 0.606 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 0.3162 | 12296.0 | 18525.7 | 2822.7 | -0.5 | 0.720 | 0.664 | 2.714 | HCC1806 QL-V-107 0 2 |