Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | AZD8055 | 3 | 72 | 0.001 | 6096.0 | 6533.6 | 1943.1 | -3.0 | 0.922 | 0.933 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.0032 | 6102.0 | 6533.6 | 1943.1 | -2.49 | 0.923 | 0.934 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.0032 | 5579.0 | 6533.6 | 1943.1 | -2.49 | 0.827 | 0.854 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.01 | 5184.0 | 6533.6 | 1943.1 | -2.0 | 0.752 | 0.793 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.01 | 5444.0 | 6533.6 | 1943.1 | -2.0 | 0.802 | 0.833 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.0316 | 4110.0 | 6533.6 | 1943.1 | -1.5 | 0.534 | 0.629 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.0316 | 3966.0 | 6533.6 | 1943.1 | -1.5 | 0.504 | 0.607 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.1 | 3167.0 | 6533.6 | 1943.1 | -1.0 | 0.322 | 0.485 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.1 | 3513.0 | 6533.6 | 1943.1 | -1.0 | 0.403 | 0.538 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.3162 | 2859.0 | 6533.6 | 1943.1 | -0.5 | 0.247 | 0.438 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.3162 | 2789.0 | 6533.6 | 1943.1 | -0.5 | 0.229 | 0.427 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.3162 | 2685.0 | 6533.6 | 1943.1 | -0.5 | 0.203 | 0.411 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 1.0 | 2541.0 | 6533.6 | 1943.1 | 0.0 | 0.166 | 0.389 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 3.1623 | 2571.0 | 6533.6 | 1943.1 | 0.5 | 0.174 | 0.394 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 3.1623 | 2404.0 | 6533.6 | 1943.1 | 0.5 | 0.129 | 0.368 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 3.1623 | 2446.0 | 6533.6 | 1943.1 | 0.5 | 0.141 | 0.374 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 10.0 | 2318.0 | 6533.6 | 1943.1 | 1.0 | 0.106 | 0.355 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 10.0 | 2011.0 | 6533.6 | 1943.1 | 1.0 | 0.020 | 0.308 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.001 | 6490.0 | 6533.6 | 1943.1 | -3.0 | 0.992 | 0.993 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.001 | 6226.0 | 6533.6 | 1943.1 | -3.0 | 0.946 | 0.953 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.001 | 6013.0 | 6533.6 | 1943.1 | -3.0 | 0.907 | 0.920 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.001 | 6136.0 | 6533.6 | 1943.1 | -3.0 | 0.929 | 0.939 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.0032 | 6520.0 | 6533.6 | 1943.1 | -2.49 | 0.998 | 0.998 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.0316 | 5356.0 | 6533.6 | 1943.1 | -1.5 | 0.785 | 0.820 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.0316 | 4970.0 | 6533.6 | 1943.1 | -1.5 | 0.711 | 0.761 | 1.750 | HCC70 QL-IV-100 0 3 |