Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-VI-86 | 3 | 72 | 0.3162 | 4158.0 | 6533.6 | 1943.1 | -0.5 | 0.545 | 0.636 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 1.0 | 1358.0 | 6533.6 | 1943.1 | 0.0 | -0.185 | 0.208 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 1.0 | 2628.0 | 6533.6 | 1943.1 | 0.0 | 0.188 | 0.402 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 3.1623 | 584.0 | 6533.6 | 1943.1 | 0.5 | -0.497 | 0.089 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 10.0 | 393.0 | 6533.6 | 1943.1 | 1.0 | -0.599 | 0.060 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 3.1623 | 648.0 | 6533.6 | 1943.1 | 0.5 | -0.466 | 0.099 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 3.1623 | 960.0 | 6533.6 | 1943.1 | 0.5 | -0.332 | 0.147 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 3.1623 | 620.0 | 6533.6 | 1943.1 | 0.5 | -0.479 | 0.095 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 10.0 | 314.0 | 6533.6 | 1943.1 | 1.0 | -0.647 | 0.048 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 3.1623 | 622.0 | 6533.6 | 1943.1 | 0.5 | -0.479 | 0.095 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 10.0 | 353.0 | 6533.6 | 1943.1 | 1.0 | -0.623 | 0.054 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 10.0 | 383.0 | 6533.6 | 1943.1 | 1.0 | -0.605 | 0.059 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 0.001 | 6629.0 | 6533.6 | 1943.1 | -3.0 | 1.020 | 1.010 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 0.001 | 6159.0 | 6533.6 | 1943.1 | -3.0 | 0.934 | 0.943 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 0.001 | 6194.0 | 6533.6 | 1943.1 | -3.0 | 0.940 | 0.948 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 0.001 | 6565.0 | 6533.6 | 1943.1 | -3.0 | 1.010 | 1.000 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 0.0032 | 6441.0 | 6533.6 | 1943.1 | -2.49 | 0.984 | 0.986 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 0.0032 | 5846.0 | 6533.6 | 1943.1 | -2.49 | 0.877 | 0.895 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 0.0032 | 6440.0 | 6533.6 | 1943.1 | -2.49 | 0.984 | 0.986 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 0.0032 | 6238.0 | 6533.6 | 1943.1 | -2.49 | 0.948 | 0.955 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 0.01 | 6276.0 | 6533.6 | 1943.1 | -2.0 | 0.955 | 0.961 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 0.01 | 6250.0 | 6533.6 | 1943.1 | -2.0 | 0.950 | 0.957 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 0.01 | 6088.0 | 6533.6 | 1943.1 | -2.0 | 0.921 | 0.932 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.01 | 6407.0 | 6533.6 | 1943.1 | -2.0 | 0.978 | 0.981 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.01 | 6171.0 | 6533.6 | 1943.1 | -2.0 | 0.936 | 0.944 | 1.750 | HCC70 QL-XII-47 0 3 |