Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-XII-108 | 1 | 72 | 0.1 | 18264.0 | 17793.8 | 2895.7 | -1.0 | 1.020 | 1.030 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.0032 | 7694.0 | 7580.8 | 2503.8 | -2.49 | 1.020 | 1.010 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.01 | 18986.0 | 18525.7 | 2822.7 | -2.0 | 1.020 | 1.020 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.01 | 19154.0 | 18525.7 | 2822.7 | -2.0 | 1.020 | 1.030 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.1 | 18911.0 | 18525.7 | 2822.7 | -1.0 | 1.020 | 1.020 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-IV-100 | 3 | 72 | 0.001 | 14793.0 | 14413.7 | 2222.1 | -3.0 | 1.020 | 1.030 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.001 | 14758.0 | 14413.7 | 2222.1 | -3.0 | 1.020 | 1.020 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.01 | 14839.0 | 14413.7 | 2222.1 | -2.0 | 1.020 | 1.030 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.3162 | 14748.0 | 14413.7 | 2222.1 | -0.5 | 1.020 | 1.020 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.001 | 18295.0 | 17793.8 | 2895.7 | -3.0 | 1.020 | 1.030 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.01 | 18203.0 | 17793.8 | 2895.7 | -2.0 | 1.020 | 1.020 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.0316 | 18154.0 | 17793.8 | 2895.7 | -1.5 | 1.020 | 1.020 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.1 | 18288.0 | 17793.8 | 2895.7 | -1.0 | 1.020 | 1.030 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.1 | 18164.0 | 17793.8 | 2895.7 | -1.0 | 1.020 | 1.020 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.01 | 19102.0 | 18525.7 | 2822.7 | -2.0 | 1.020 | 1.030 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.0316 | 19080.0 | 18525.7 | 2822.7 | -1.5 | 1.020 | 1.030 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.0316 | 19036.0 | 18525.7 | 2822.7 | -1.5 | 1.020 | 1.030 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 3 | 72 | 0.0032 | 14718.0 | 14413.7 | 2222.1 | -2.49 | 1.020 | 1.020 | 2.697 | HCC1806 QL-XII-47 0 3 |
| HCC1806 | QL-XII-47 | 3 | 72 | 0.01 | 14766.0 | 14413.7 | 2222.1 | -2.0 | 1.020 | 1.020 | 2.697 | HCC1806 QL-XII-47 0 3 |
| HCC1806 | QL-XII-47 | 3 | 72 | 0.0316 | 14831.0 | 14413.7 | 2222.1 | -1.5 | 1.020 | 1.030 | 2.697 | HCC1806 QL-XII-47 0 3 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.0032 | 7700.0 | 7580.8 | 2503.8 | -2.49 | 1.020 | 1.020 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.001 | 7695.0 | 7580.8 | 2503.8 | -3.0 | 1.020 | 1.020 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.001 | 18181.0 | 17793.8 | 2895.7 | -3.0 | 1.020 | 1.020 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.0032 | 18275.0 | 17793.8 | 2895.7 | -2.49 | 1.020 | 1.030 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.0316 | 18184.0 | 17793.8 | 2895.7 | -1.5 | 1.020 | 1.020 | 2.619 | HCC1806 QL-XII-61 0 1 |