Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-VIII-58 | 3 | 72 | 3.1623 | 98.0 | 6533.6 | 1943.1 | 0.5 | -0.819 | 0.015 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-XII-47 | 2 | 72 | 10.0 | 177.0 | 7167.9 | 2409.0 | 1.0 | -0.810 | 0.025 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | Torin2 | 2 | 72 | 1.0 | 178.0 | 7167.9 | 2409.0 | 0.0 | -0.809 | 0.025 | 1.573 | HCC70 Torin2 0 2 |
| HCC1806 | QL-XII-47 | 3 | 72 | 10.0 | 26.0 | 14413.7 | 2222.1 | 1.0 | -0.808 | 0.002 | 2.697 | HCC1806 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 1 | 72 | 10.0 | 186.0 | 7580.8 | 2503.8 | 1.0 | -0.803 | 0.025 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-VIII-58 | 3 | 72 | 3.1623 | 116.0 | 6533.6 | 1943.1 | 0.5 | -0.800 | 0.018 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC1806 | QL-XII-47 | 3 | 72 | 10.0 | 32.0 | 14413.7 | 2222.1 | 1.0 | -0.792 | 0.002 | 2.697 | HCC1806 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 1 | 72 | 10.0 | 209.0 | 7580.8 | 2503.8 | 1.0 | -0.789 | 0.028 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | Torin2 | 2 | 72 | 1.0 | 209.0 | 7167.9 | 2409.0 | 0.0 | -0.789 | 0.029 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | QL-XII-47 | 1 | 72 | 10.0 | 228.0 | 7580.8 | 2503.8 | 1.0 | -0.777 | 0.030 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | Torin2 | 2 | 72 | 1.0 | 233.0 | 7167.9 | 2409.0 | 0.0 | -0.773 | 0.033 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 1.0 | 241.0 | 7167.9 | 2409.0 | 0.0 | -0.769 | 0.034 | 1.573 | HCC70 Torin2 0 2 |
| HCC1806 | QL-VIII-58 | 3 | 72 | 10.0 | 43.0 | 14413.7 | 2222.1 | 1.0 | -0.768 | 0.003 | 2.697 | HCC1806 QL-VIII-58 0 3 |
| HCC1806 | QL-VIII-58 | 3 | 72 | 10.0 | 45.0 | 14413.7 | 2222.1 | 1.0 | -0.764 | 0.003 | 2.697 | HCC1806 QL-VIII-58 0 3 |
| HCC1806 | QL-VIII-58 | 3 | 72 | 10.0 | 46.0 | 14413.7 | 2222.1 | 1.0 | -0.762 | 0.003 | 2.697 | HCC1806 QL-VIII-58 0 3 |
| HCC70 | QL-IV-100 | 2 | 72 | 10.0 | 259.0 | 7167.9 | 2409.0 | 1.0 | -0.758 | 0.036 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | Torin2 | 1 | 72 | 1.0 | 263.0 | 7580.8 | 2503.8 | 0.0 | -0.756 | 0.035 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 1.0 | 265.0 | 7580.8 | 2503.8 | 0.0 | -0.755 | 0.035 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 1.0 | 268.0 | 7580.8 | 2503.8 | 0.0 | -0.753 | 0.035 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | QL-IV-100 | 2 | 72 | 10.0 | 269.0 | 7167.9 | 2409.0 | 1.0 | -0.752 | 0.038 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 10.0 | 275.0 | 7167.9 | 2409.0 | 1.0 | -0.748 | 0.038 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 10.0 | 289.0 | 7167.9 | 2409.0 | 1.0 | -0.740 | 0.040 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC1806 | QL-VIII-58 | 3 | 72 | 10.0 | 60.0 | 14413.7 | 2222.1 | 1.0 | -0.738 | 0.004 | 2.697 | HCC1806 QL-VIII-58 0 3 |
| HCC1806 | QL-XII-47 | 3 | 72 | 10.0 | 61.0 | 14413.7 | 2222.1 | 1.0 | -0.736 | 0.004 | 2.697 | HCC1806 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 10.0 | 192.0 | 6533.6 | 1943.1 | 1.0 | -0.734 | 0.029 | 1.750 | HCC70 QL-XII-47 0 3 |