Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | Torin2 | 3 | 72 | 10.0 | 15.0 | 6533.6 | 1943.1 | 1.0 | -0.938 | 0.002 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 10.0 | 16.0 | 6533.6 | 1943.1 | 1.0 | -0.936 | 0.002 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 10.0 | 21.0 | 6533.6 | 1943.1 | 1.0 | -0.925 | 0.003 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | QL-VIII-58 | 2 | 72 | 3.1623 | 43.0 | 7167.9 | 2409.0 | 0.5 | -0.923 | 0.006 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | Torin2 | 1 | 72 | 3.1623 | 43.0 | 7580.8 | 2503.8 | 0.5 | -0.921 | 0.006 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 10.0 | 44.0 | 7580.8 | 2503.8 | 1.0 | -0.920 | 0.006 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 3.1623 | 46.0 | 7580.8 | 2503.8 | 0.5 | -0.918 | 0.006 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | QL-VIII-58 | 2 | 72 | 3.1623 | 48.0 | 7167.9 | 2409.0 | 0.5 | -0.917 | 0.007 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 1 | 72 | 3.1623 | 48.0 | 7580.8 | 2503.8 | 0.5 | -0.916 | 0.006 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | Torin2 | 1 | 72 | 3.1623 | 49.0 | 7580.8 | 2503.8 | 0.5 | -0.915 | 0.006 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 3 | 72 | 3.1623 | 27.0 | 6533.6 | 1943.1 | 0.5 | -0.913 | 0.004 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 1 | 72 | 3.1623 | 52.0 | 7580.8 | 2503.8 | 0.5 | -0.911 | 0.007 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 3.1623 | 54.0 | 7580.8 | 2503.8 | 0.5 | -0.909 | 0.007 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | Torin2 | 3 | 72 | 3.1623 | 30.0 | 6533.6 | 1943.1 | 0.5 | -0.908 | 0.005 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | QL-VIII-58 | 2 | 72 | 3.1623 | 59.0 | 7167.9 | 2409.0 | 0.5 | -0.905 | 0.008 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | Torin2 | 3 | 72 | 3.1623 | 33.0 | 6533.6 | 1943.1 | 0.5 | -0.903 | 0.005 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | QL-VIII-58 | 1 | 72 | 3.1623 | 61.0 | 7580.8 | 2503.8 | 0.5 | -0.902 | 0.008 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 3.1623 | 64.0 | 7580.8 | 2503.8 | 0.5 | -0.899 | 0.008 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | Torin2 | 3 | 72 | 3.1623 | 40.0 | 6533.6 | 1943.1 | 0.5 | -0.891 | 0.006 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | QL-XII-47 | 1 | 72 | 10.0 | 113.0 | 7580.8 | 2503.8 | 1.0 | -0.856 | 0.015 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 2 | 72 | 10.0 | 159.0 | 7167.9 | 2409.0 | 1.0 | -0.822 | 0.022 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | QL-VIII-58 | 3 | 72 | 3.1623 | 96.0 | 6533.6 | 1943.1 | 0.5 | -0.821 | 0.015 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-XII-47 | 2 | 72 | 10.0 | 163.0 | 7167.9 | 2409.0 | 1.0 | -0.820 | 0.023 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | QL-XII-47 | 2 | 72 | 10.0 | 163.0 | 7167.9 | 2409.0 | 1.0 | -0.820 | 0.023 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | QL-VIII-58 | 3 | 72 | 3.1623 | 98.0 | 6533.6 | 1943.1 | 0.5 | -0.819 | 0.015 | 1.750 | HCC70 QL-VIII-58 0 3 |