Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-IV-100 | 1 | 72 | 10.0 | 1250.0 | 17793.8 | 2895.7 | 1.0 | -0.274 | 0.070 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC70 | QL-V-73 | 2 | 72 | 3.1623 | 1463.0 | 7167.9 | 2409.0 | 0.5 | -0.272 | 0.204 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 10.0 | 1463.0 | 7167.9 | 2409.0 | 1.0 | -0.272 | 0.204 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 10.0 | 1462.0 | 7167.9 | 2409.0 | 1.0 | -0.272 | 0.204 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC1806 | QL-XII-47 | 1 | 72 | 3.1623 | 1264.0 | 17793.8 | 2895.7 | 0.5 | -0.271 | 0.071 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-IV-100 | 2 | 72 | 3.1623 | 1201.0 | 18525.7 | 2822.7 | 0.5 | -0.270 | 0.065 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 10.0 | 1204.0 | 18525.7 | 2822.7 | 1.0 | -0.269 | 0.065 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 1.0 | 1207.0 | 18525.7 | 2822.7 | 0.0 | -0.269 | 0.065 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 1.0 | 1211.0 | 18525.7 | 2822.7 | 0.0 | -0.268 | 0.065 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | QL-XII-47 | 1 | 72 | 3.1623 | 1281.0 | 17793.8 | 2895.7 | 0.5 | -0.268 | 0.072 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 10.0 | 1289.0 | 17793.8 | 2895.7 | 1.0 | -0.266 | 0.072 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 3.1623 | 1221.0 | 18525.7 | 2822.7 | 0.5 | -0.266 | 0.066 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 3.1623 | 1229.0 | 18525.7 | 2822.7 | 0.5 | -0.264 | 0.066 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 3.1623 | 1231.0 | 18525.7 | 2822.7 | 0.5 | -0.263 | 0.066 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | QL-IV-100 | 3 | 72 | 10.0 | 975.0 | 14413.7 | 2222.1 | 1.0 | -0.263 | 0.068 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 1.0 | 1142.0 | 6533.6 | 1943.1 | 0.0 | -0.262 | 0.175 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 1 | 72 | 1.0 | 1549.0 | 7580.8 | 2503.8 | 0.0 | -0.260 | 0.204 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 2 | 72 | 3.1623 | 1251.0 | 18525.7 | 2822.7 | 0.5 | -0.259 | 0.068 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC70 | QL-VIII-58 | 3 | 72 | 1.0 | 1153.0 | 6533.6 | 1943.1 | 0.0 | -0.258 | 0.176 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-V-107 | 1 | 72 | 1.0 | 1562.0 | 7580.8 | 2503.8 | 0.0 | -0.256 | 0.206 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC1806 | Torin2 | 2 | 72 | 3.1623 | 1264.0 | 18525.7 | 2822.7 | 0.5 | -0.256 | 0.068 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 10.0 | 1269.0 | 18525.7 | 2822.7 | 1.0 | -0.255 | 0.069 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 10.0 | 1273.0 | 18525.7 | 2822.7 | 1.0 | -0.254 | 0.069 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 3.1623 | 1273.0 | 18525.7 | 2822.7 | 0.5 | -0.254 | 0.069 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 10.0 | 1288.0 | 18525.7 | 2822.7 | 1.0 | -0.251 | 0.070 | 2.714 | HCC1806 QL-IV-100 0 2 |