Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-IV-100 | 3 | 72 | 10.0 | 871.0 | 14413.7 | 2222.1 | 1.0 | -0.293 | 0.060 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 2 | 72 | 1.0 | 1399.0 | 7167.9 | 2409.0 | 0.0 | -0.292 | 0.195 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC1806 | QL-IV-100 | 1 | 72 | 3.1623 | 1172.0 | 17793.8 | 2895.7 | 0.5 | -0.292 | 0.066 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC70 | QL-X-138 | 2 | 72 | 10.0 | 1401.0 | 7167.9 | 2409.0 | 1.0 | -0.291 | 0.195 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 1.0 | 1402.0 | 7167.9 | 2409.0 | 0.0 | -0.291 | 0.196 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC1806 | QL-V-107 | 1 | 72 | 10.0 | 1175.0 | 17793.8 | 2895.7 | 1.0 | -0.291 | 0.066 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | Torin2 | 3 | 72 | 3.1623 | 881.0 | 14413.7 | 2222.1 | 0.5 | -0.290 | 0.061 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 1 | 72 | 3.1623 | 1180.0 | 17793.8 | 2895.7 | 0.5 | -0.290 | 0.066 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 3.1623 | 1121.0 | 18525.7 | 2822.7 | 0.5 | -0.288 | 0.061 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-IV-100 | 1 | 72 | 10.0 | 1190.0 | 17793.8 | 2895.7 | 1.0 | -0.288 | 0.067 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | Torin2 | 1 | 72 | 1.0 | 1195.0 | 17793.8 | 2895.7 | 0.0 | -0.287 | 0.067 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | QL-V-107 | 2 | 72 | 10.0 | 1130.0 | 18525.7 | 2822.7 | 1.0 | -0.286 | 0.061 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 10.0 | 1131.0 | 18525.7 | 2822.7 | 1.0 | -0.286 | 0.061 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | Torin2 | 1 | 72 | 1.0 | 1201.0 | 17793.8 | 2895.7 | 0.0 | -0.285 | 0.068 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | Torin2 | 3 | 72 | 3.1623 | 899.0 | 14413.7 | 2222.1 | 0.5 | -0.285 | 0.062 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | QL-IV-100 | 2 | 72 | 3.1623 | 1139.0 | 18525.7 | 2822.7 | 0.5 | -0.284 | 0.062 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC70 | QL-VIII-58 | 1 | 72 | 1.0 | 1469.0 | 7580.8 | 2503.8 | 0.0 | -0.284 | 0.194 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC1806 | Torin2 | 3 | 72 | 1.0 | 908.0 | 14413.7 | 2222.1 | 0.0 | -0.282 | 0.063 | 2.697 | HCC1806 Torin2 0 3 |
| HCC70 | QL-V-73 | 2 | 72 | 3.1623 | 1439.0 | 7167.9 | 2409.0 | 0.5 | -0.279 | 0.201 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 1.0 | 1439.0 | 7167.9 | 2409.0 | 0.0 | -0.279 | 0.201 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 1.0 | 1166.0 | 18525.7 | 2822.7 | 0.0 | -0.278 | 0.063 | 2.714 | HCC1806 Torin2 0 2 |
| HCC70 | Torin1 | 2 | 72 | 10.0 | 1445.0 | 7167.9 | 2409.0 | 1.0 | -0.277 | 0.202 | 1.573 | HCC70 Torin1 0 2 |
| HCC1806 | Torin2 | 3 | 72 | 1.0 | 926.0 | 14413.7 | 2222.1 | 0.0 | -0.277 | 0.064 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 1 | 72 | 3.1623 | 1239.0 | 17793.8 | 2895.7 | 0.5 | -0.277 | 0.070 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | QL-IV-100 | 3 | 72 | 3.1623 | 934.0 | 14413.7 | 2222.1 | 0.5 | -0.275 | 0.065 | 2.697 | HCC1806 QL-IV-100 0 3 |