Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-IV-100 | 3 | 72 | 3.1623 | 805.0 | 14413.7 | 2222.1 | 0.5 | -0.314 | 0.056 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 1.0 | 806.0 | 14413.7 | 2222.1 | 0.0 | -0.313 | 0.056 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 10.0 | 810.0 | 14413.7 | 2222.1 | 1.0 | -0.312 | 0.056 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC70 | QL-V-107 | 2 | 72 | 1.0 | 1342.0 | 7167.9 | 2409.0 | 0.0 | -0.311 | 0.187 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | Torin1 | 2 | 72 | 10.0 | 1345.0 | 7167.9 | 2409.0 | 1.0 | -0.310 | 0.188 | 1.573 | HCC70 Torin1 0 2 |
| HCC1806 | QL-IV-100 | 1 | 72 | 3.1623 | 1098.0 | 17793.8 | 2895.7 | 0.5 | -0.309 | 0.062 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC70 | QL-X-138 | 2 | 72 | 10.0 | 1348.0 | 7167.9 | 2409.0 | 1.0 | -0.309 | 0.188 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC1806 | Torin2 | 3 | 72 | 3.1623 | 821.0 | 14413.7 | 2222.1 | 0.5 | -0.309 | 0.057 | 2.697 | HCC1806 Torin2 0 3 |
| HCC70 | QL-V-107 | 2 | 72 | 1.0 | 1347.0 | 7167.9 | 2409.0 | 0.0 | -0.309 | 0.188 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 1.0 | 1353.0 | 7167.9 | 2409.0 | 0.0 | -0.307 | 0.189 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-IV-100 | 3 | 72 | 1.0 | 1027.0 | 6533.6 | 1943.1 | 0.0 | -0.305 | 0.157 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC1806 | Torin2 | 1 | 72 | 1.0 | 1119.0 | 17793.8 | 2895.7 | 0.0 | -0.304 | 0.063 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | Torin2 | 1 | 72 | 3.1623 | 1125.0 | 17793.8 | 2895.7 | 0.5 | -0.303 | 0.063 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | QL-IV-100 | 3 | 72 | 3.1623 | 844.0 | 14413.7 | 2222.1 | 0.5 | -0.302 | 0.059 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-XII-47 | 2 | 72 | 3.1623 | 1062.0 | 18525.7 | 2822.7 | 0.5 | -0.302 | 0.057 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | Torin2 | 3 | 72 | 3.1623 | 847.0 | 14413.7 | 2222.1 | 0.5 | -0.301 | 0.059 | 2.697 | HCC1806 Torin2 0 3 |
| HCC70 | QL-IV-100 | 1 | 72 | 1.0 | 1415.0 | 7580.8 | 2503.8 | 0.0 | -0.300 | 0.187 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC1806 | Torin2 | 2 | 72 | 1.0 | 1071.0 | 18525.7 | 2822.7 | 0.0 | -0.300 | 0.058 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 3.1623 | 1074.0 | 18525.7 | 2822.7 | 0.5 | -0.300 | 0.058 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | Torin2 | 3 | 72 | 1.0 | 863.0 | 14413.7 | 2222.1 | 0.0 | -0.296 | 0.060 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 3.1623 | 866.0 | 14413.7 | 2222.1 | 0.5 | -0.295 | 0.060 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | Torin2 | 1 | 72 | 3.1623 | 1160.0 | 17793.8 | 2895.7 | 0.5 | -0.295 | 0.065 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 3.1623 | 1165.0 | 17793.8 | 2895.7 | 0.5 | -0.294 | 0.066 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-XII-47 | 2 | 72 | 3.1623 | 1099.0 | 18525.7 | 2822.7 | 0.5 | -0.294 | 0.059 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 10.0 | 1101.0 | 18525.7 | 2822.7 | 1.0 | -0.293 | 0.059 | 2.714 | HCC1806 QL-V-107 0 2 |