Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-IV-100 | 2 | 72 | 1.0 | 1201.0 | 7167.9 | 2409.0 | 0.0 | -0.358 | 0.168 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | Torin2 | 3 | 72 | 0.3162 | 895.0 | 6533.6 | 1943.1 | -0.5 | -0.358 | 0.137 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | QL-IV-100 | 2 | 72 | 1.0 | 1208.0 | 7167.9 | 2409.0 | 0.0 | -0.355 | 0.169 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC1806 | QL-V-107 | 3 | 72 | 10.0 | 683.0 | 14413.7 | 2222.1 | 1.0 | -0.354 | 0.047 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC70 | QL-VIII-58 | 2 | 72 | 1.0 | 1224.0 | 7167.9 | 2409.0 | 0.0 | -0.350 | 0.171 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VI-86 | 3 | 72 | 3.1623 | 917.0 | 6533.6 | 1943.1 | 0.5 | -0.349 | 0.140 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 3.1623 | 950.0 | 17793.8 | 2895.7 | 0.5 | -0.347 | 0.053 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 2 | 72 | 1.0 | 1243.0 | 7167.9 | 2409.0 | 0.0 | -0.343 | 0.173 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC1806 | QL-V-107 | 3 | 72 | 10.0 | 732.0 | 14413.7 | 2222.1 | 1.0 | -0.337 | 0.051 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 10.0 | 736.0 | 14413.7 | 2222.1 | 1.0 | -0.336 | 0.051 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 3.1623 | 960.0 | 6533.6 | 1943.1 | 0.5 | -0.332 | 0.147 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 10.0 | 751.0 | 14413.7 | 2222.1 | 1.0 | -0.331 | 0.052 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-V-107 | 1 | 72 | 10.0 | 1018.0 | 17793.8 | 2895.7 | 1.0 | -0.329 | 0.057 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC70 | Torin1 | 2 | 72 | 10.0 | 1286.0 | 7167.9 | 2409.0 | 1.0 | -0.329 | 0.179 | 1.573 | HCC70 Torin1 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 3.1623 | 967.0 | 18525.7 | 2822.7 | 0.5 | -0.326 | 0.052 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC70 | Torin2 | 3 | 72 | 0.3162 | 976.0 | 6533.6 | 1943.1 | -0.5 | -0.325 | 0.149 | 1.750 | HCC70 Torin2 0 3 |
| HCC1806 | QL-V-107 | 1 | 72 | 10.0 | 1047.0 | 17793.8 | 2895.7 | 1.0 | -0.322 | 0.059 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 1.0 | 1349.0 | 7580.8 | 2503.8 | 0.0 | -0.321 | 0.178 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC1806 | Torin2 | 1 | 72 | 1.0 | 1059.0 | 17793.8 | 2895.7 | 0.0 | -0.319 | 0.060 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | QL-XII-47 | 2 | 72 | 3.1623 | 996.0 | 18525.7 | 2822.7 | 0.5 | -0.319 | 0.054 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 3.1623 | 1058.0 | 17793.8 | 2895.7 | 0.5 | -0.319 | 0.060 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 1.0 | 1360.0 | 7580.8 | 2503.8 | 0.0 | -0.317 | 0.179 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 10.0 | 1071.0 | 17793.8 | 2895.7 | 1.0 | -0.316 | 0.060 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 3.1623 | 1071.0 | 17793.8 | 2895.7 | 0.5 | -0.316 | 0.060 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-IV-100 | 3 | 72 | 3.1623 | 805.0 | 14413.7 | 2222.1 | 0.5 | -0.314 | 0.056 | 2.697 | HCC1806 QL-IV-100 0 3 |