Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-XII-108 | 2 | 72 | 0.1 | 7821.0 | 7167.9 | 2409.0 | -1.0 | 1.110 | 1.090 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC70 | QL-XII-47 | 2 | 72 | 0.001 | 7826.0 | 7167.9 | 2409.0 | -3.0 | 1.110 | 1.090 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.0032 | 7844.0 | 7167.9 | 2409.0 | -2.49 | 1.120 | 1.090 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.0316 | 19318.0 | 17793.8 | 2895.7 | -1.5 | 1.060 | 1.090 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC70 | QL-XII-108 | 2 | 72 | 0.01 | 7738.0 | 7167.9 | 2409.0 | -2.0 | 1.100 | 1.080 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 0.0032 | 19989.0 | 18525.7 | 2822.7 | -2.49 | 1.060 | 1.080 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.0316 | 7762.0 | 7167.9 | 2409.0 | -1.5 | 1.100 | 1.080 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.1 | 7754.0 | 7167.9 | 2409.0 | -1.0 | 1.100 | 1.080 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC1806 | QL-X-138 | 3 | 72 | 0.0032 | 15631.0 | 14413.7 | 2222.1 | -2.49 | 1.060 | 1.080 | 2.697 | HCC1806 QL-X-138 0 3 |
| HCC70 | Torin1 | 1 | 72 | 0.001 | 8154.0 | 7580.8 | 2503.8 | -3.0 | 1.090 | 1.080 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.001 | 7711.0 | 7167.9 | 2409.0 | -3.0 | 1.100 | 1.080 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.01 | 7734.0 | 7167.9 | 2409.0 | -2.0 | 1.100 | 1.080 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.01 | 7772.0 | 7167.9 | 2409.0 | -2.0 | 1.110 | 1.080 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.0032 | 8185.0 | 7580.8 | 2503.8 | -2.49 | 1.100 | 1.080 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.0032 | 8198.0 | 7580.8 | 2503.8 | -2.49 | 1.100 | 1.080 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-X-138 | 2 | 72 | 0.01 | 7762.0 | 7167.9 | 2409.0 | -2.0 | 1.100 | 1.080 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC1806 | QL-X-138 | 3 | 72 | 0.0316 | 15520.0 | 14413.7 | 2222.1 | -1.5 | 1.060 | 1.080 | 2.697 | HCC1806 QL-X-138 0 3 |
| HCC1806 | QL-XII-47 | 3 | 72 | 0.1 | 15591.0 | 14413.7 | 2222.1 | -1.0 | 1.060 | 1.080 | 2.697 | HCC1806 QL-XII-47 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.0032 | 15502.0 | 14413.7 | 2222.1 | -2.49 | 1.050 | 1.080 | 2.697 | HCC1806 Torin1 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.01 | 7006.0 | 6533.6 | 1943.1 | -2.0 | 1.080 | 1.070 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC1806 | QL-X-138 | 2 | 72 | 0.0032 | 19814.0 | 18525.7 | 2822.7 | -2.49 | 1.050 | 1.070 | 2.714 | HCC1806 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.001 | 7677.0 | 7167.9 | 2409.0 | -3.0 | 1.090 | 1.070 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 1 | 72 | 0.001 | 8107.0 | 7580.8 | 2503.8 | -3.0 | 1.090 | 1.070 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | QL-XII-47 | 2 | 72 | 0.0032 | 7670.0 | 7167.9 | 2409.0 | -2.49 | 1.090 | 1.070 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.01 | 6993.0 | 6533.6 | 1943.1 | -2.0 | 1.080 | 1.070 | 1.750 | HCC70 QL-XII-108 0 3 |