Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | Torin2 | 3 | 72 | 0.0032 | 5535.0 | 6533.6 | 1943.1 | -2.49 | 0.819 | 0.847 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 0.0032 | 4952.0 | 6533.6 | 1943.1 | -2.49 | 0.707 | 0.758 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 0.001 | 6199.0 | 6533.6 | 1943.1 | -3.0 | 0.941 | 0.949 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 3.1623 | 30.0 | 6533.6 | 1943.1 | 0.5 | -0.908 | 0.005 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 1.0 | 255.0 | 6533.6 | 1943.1 | 0.0 | -0.687 | 0.039 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 0.0032 | 5135.0 | 6533.6 | 1943.1 | -2.49 | 0.743 | 0.786 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 0.0316 | 3078.0 | 6533.6 | 1943.1 | -1.5 | 0.301 | 0.471 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 0.0316 | 3084.0 | 6533.6 | 1943.1 | -1.5 | 0.302 | 0.472 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 0.0316 | 3296.0 | 6533.6 | 1943.1 | -1.5 | 0.353 | 0.504 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 0.1 | 2220.0 | 6533.6 | 1943.1 | -1.0 | 0.079 | 0.340 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 0.1 | 2501.0 | 6533.6 | 1943.1 | -1.0 | 0.155 | 0.383 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 2 | 72 | 0.01 | 4457.0 | 7167.9 | 2409.0 | -2.0 | 0.479 | 0.622 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.0032 | 6063.0 | 7167.9 | 2409.0 | -2.49 | 0.798 | 0.846 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.01 | 4295.0 | 7167.9 | 2409.0 | -2.0 | 0.444 | 0.599 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.0032 | 5558.0 | 7167.9 | 2409.0 | -2.49 | 0.701 | 0.775 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.0032 | 5346.0 | 7167.9 | 2409.0 | -2.49 | 0.660 | 0.746 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.0032 | 5584.0 | 7167.9 | 2409.0 | -2.49 | 0.706 | 0.779 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.01 | 4787.0 | 7167.9 | 2409.0 | -2.0 | 0.547 | 0.668 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.001 | 5960.0 | 7167.9 | 2409.0 | -3.0 | 0.779 | 0.831 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.001 | 7033.0 | 7167.9 | 2409.0 | -3.0 | 0.976 | 0.981 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.001 | 6072.0 | 7167.9 | 2409.0 | -3.0 | 0.800 | 0.847 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.01 | 4609.0 | 7167.9 | 2409.0 | -2.0 | 0.510 | 0.643 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.001 | 6489.0 | 7167.9 | 2409.0 | -3.0 | 0.877 | 0.905 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 10.0 | 14.0 | 7167.9 | 2409.0 | 1.0 | -0.962 | 0.002 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 10.0 | 28.0 | 7167.9 | 2409.0 | 1.0 | -0.941 | 0.004 | 1.573 | HCC70 Torin2 0 2 |