Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)

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Cell line Drug name Experimental replicate Timepoint Drug concentration Live cell count Average live cell count, DMSO control Average live cell count (time = 0) Log10(drug concentration) GR value Relative cell count (treatment versus DMSO) Cell doublings (DMSO control) Experiment name
HCC1806 AZD8055 2 72
0.001
 17923.0 18525.7 2822.7
-3.0
 0.976 0.967 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.0032
 11898.0 18525.7 2822.7
-2.49
 0.699 0.642 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.0032
 18039.0 18525.7 2822.7
-2.49
 0.980 0.974 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.01
 17226.0 18525.7 2822.7
-2.0
 0.947 0.930 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.01
 17722.0 18525.7 2822.7
-2.0
 0.968 0.957 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.0316
 15618.0 18525.7 2822.7
-1.5
 0.878 0.843 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.0316
 15293.0 18525.7 2822.7
-1.5
 0.864 0.826 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.1
 12142.0 18525.7 2822.7
-1.0
 0.712 0.655 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.1
 12244.0 18525.7 2822.7
-1.0
 0.717 0.661 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.3162
 9698.0 18525.7 2822.7
-0.5
 0.576 0.523 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.3162
 9550.0 18525.7 2822.7
-0.5
 0.567 0.516 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.3162
 9071.0 18525.7 2822.7
-0.5
 0.537 0.490 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
1.0
 8645.0 18525.7 2822.7
0.0
 0.510 0.467 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
3.1623
 7972.0 18525.7 2822.7
0.5
 0.466 0.430 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
3.1623
 7967.0 18525.7 2822.7
0.5
 0.466 0.430 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
3.1623
 7955.0 18525.7 2822.7
0.5
 0.465 0.429 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
10.0
 7623.0 18525.7 2822.7
1.0
 0.442 0.411 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
10.0
 7347.0 18525.7 2822.7
1.0
 0.423 0.397 2.714
HCC1806 AZD8055 0 2
HCC1806 QL-IV-100 2 72
0.001
 18167.0 18525.7 2822.7
-3.0
 0.986 0.981 2.714
HCC1806 QL-IV-100 0 2
HCC1806 QL-IV-100 2 72
0.001
 18295.0 18525.7 2822.7
-3.0
 0.991 0.988 2.714
HCC1806 QL-IV-100 0 2
HCC1806 QL-IV-100 2 72
0.001
 18083.0 18525.7 2822.7
-3.0
 0.982 0.976 2.714
HCC1806 QL-IV-100 0 2
HCC1806 AZD8055 2 72
0.001
 18210.0 18525.7 2822.7
-3.0
 0.987 0.983 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.0032
 18499.0 18525.7 2822.7
-2.49
 0.999 0.999 2.714
HCC1806 AZD8055 0 2
HCC1806 QL-IV-100 2 72
0.0316
 16887.0 18525.7 2822.7
-1.5
 0.933 0.912 2.714
HCC1806 QL-IV-100 0 2
HCC1806 QL-IV-100 2 72
0.0316
 17567.0 18525.7 2822.7
-1.5
 0.961 0.948 2.714
HCC1806 QL-IV-100 0 2