Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-XII-108 | 2 | 72 | 0.01 | 7738.0 | 7167.9 | 2409.0 | -2.0 | 1.100 | 1.080 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC70 | QL-V-73 | 3 | 72 | 0.0032 | 7126.0 | 6533.6 | 1943.1 | -2.49 | 1.100 | 1.090 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-X-138 | 2 | 72 | 0.0316 | 7762.0 | 7167.9 | 2409.0 | -1.5 | 1.100 | 1.080 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.01 | 7762.0 | 7167.9 | 2409.0 | -2.0 | 1.100 | 1.080 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.0032 | 8185.0 | 7580.8 | 2503.8 | -2.49 | 1.100 | 1.080 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-X-138 | 2 | 72 | 0.1 | 7754.0 | 7167.9 | 2409.0 | -1.0 | 1.100 | 1.080 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.0032 | 8198.0 | 7580.8 | 2503.8 | -2.49 | 1.100 | 1.080 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.001 | 7711.0 | 7167.9 | 2409.0 | -3.0 | 1.100 | 1.080 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | Torin1 | 1 | 72 | 0.001 | 8154.0 | 7580.8 | 2503.8 | -3.0 | 1.090 | 1.080 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | QL-X-138 | 1 | 72 | 0.001 | 8107.0 | 7580.8 | 2503.8 | -3.0 | 1.090 | 1.070 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | QL-XII-108 | 2 | 72 | 0.0032 | 7674.0 | 7167.9 | 2409.0 | -2.49 | 1.090 | 1.070 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC70 | QL-XII-47 | 2 | 72 | 0.1 | 7701.0 | 7167.9 | 2409.0 | -1.0 | 1.090 | 1.070 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 1.0 | 7700.0 | 7167.9 | 2409.0 | 0.0 | 1.090 | 1.070 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.001 | 7677.0 | 7167.9 | 2409.0 | -3.0 | 1.090 | 1.070 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.001 | 7670.0 | 7167.9 | 2409.0 | -3.0 | 1.090 | 1.070 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 1 | 72 | 0.0032 | 8144.0 | 7580.8 | 2503.8 | -2.49 | 1.090 | 1.070 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | QL-XII-47 | 2 | 72 | 0.0032 | 7670.0 | 7167.9 | 2409.0 | -2.49 | 1.090 | 1.070 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 3 | 72 | 0.0032 | 16020.0 | 14413.7 | 2222.1 | -2.49 | 1.080 | 1.110 | 2.697 | HCC1806 QL-XII-47 0 3 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.3162 | 8065.0 | 7580.8 | 2503.8 | -0.5 | 1.080 | 1.060 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.01 | 8045.0 | 7580.8 | 2503.8 | -2.0 | 1.080 | 1.060 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-V-73 | 2 | 72 | 0.01 | 7627.0 | 7167.9 | 2409.0 | -2.0 | 1.080 | 1.060 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.01 | 6993.0 | 6533.6 | 1943.1 | -2.0 | 1.080 | 1.070 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.01 | 7006.0 | 6533.6 | 1943.1 | -2.0 | 1.080 | 1.070 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.01 | 8057.0 | 7580.8 | 2503.8 | -2.0 | 1.080 | 1.060 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-V-73 | 1 | 72 | 0.001 | 8034.0 | 7580.8 | 2503.8 | -3.0 | 1.070 | 1.060 | 1.598 | HCC70 QL-V-73 0 1 |