Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
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HCC1806 | QL-X-138 | 2 | 72 | 10.0 | 5220.0 | 18525.7 | 2822.7 | 1.0 | 0.254 | 0.282 | 2.714 | HCC1806 QL-X-138 0 2 |
HCC1806 | QL-X-138 | 2 | 72 | 10.0 | 5420.0 | 18525.7 | 2822.7 | 1.0 | 0.272 | 0.293 | 2.714 | HCC1806 QL-X-138 0 2 |
HCC1806 | QL-X-138 | 2 | 72 | 10.0 | 5403.0 | 18525.7 | 2822.7 | 1.0 | 0.270 | 0.292 | 2.714 | HCC1806 QL-X-138 0 2 |
HCC1806 | QL-X-138 | 3 | 72 | 0.001 | 14349.0 | 14413.7 | 2222.1 | -3.0 | 0.997 | 0.996 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.001 | 13464.0 | 14413.7 | 2222.1 | -3.0 | 0.950 | 0.934 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.001 | 13694.0 | 14413.7 | 2222.1 | -3.0 | 0.962 | 0.950 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.001 | 14679.0 | 14413.7 | 2222.1 | -3.0 | 1.010 | 1.020 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.0032 | 14642.0 | 14413.7 | 2222.1 | -2.49 | 1.010 | 1.020 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.0032 | 14038.0 | 14413.7 | 2222.1 | -2.49 | 0.981 | 0.974 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.0032 | 15631.0 | 14413.7 | 2222.1 | -2.49 | 1.060 | 1.080 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.0032 | 14432.0 | 14413.7 | 2222.1 | -2.49 | 1.000 | 1.000 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.01 | 14993.0 | 14413.7 | 2222.1 | -2.0 | 1.030 | 1.040 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.01 | 14585.0 | 14413.7 | 2222.1 | -2.0 | 1.010 | 1.010 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.01 | 14748.0 | 14413.7 | 2222.1 | -2.0 | 1.020 | 1.020 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.01 | 15265.0 | 14413.7 | 2222.1 | -2.0 | 1.040 | 1.060 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.0316 | 13756.0 | 14413.7 | 2222.1 | -1.5 | 0.966 | 0.954 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.0316 | 14491.0 | 14413.7 | 2222.1 | -1.5 | 1.000 | 1.010 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.0316 | 13866.0 | 14413.7 | 2222.1 | -1.5 | 0.971 | 0.962 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.0316 | 15520.0 | 14413.7 | 2222.1 | -1.5 | 1.060 | 1.080 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.1 | 15156.0 | 14413.7 | 2222.1 | -1.0 | 1.040 | 1.050 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.1 | 13891.0 | 14413.7 | 2222.1 | -1.0 | 0.973 | 0.964 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.1 | 14855.0 | 14413.7 | 2222.1 | -1.0 | 1.020 | 1.030 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.1 | 14753.0 | 14413.7 | 2222.1 | -1.0 | 1.020 | 1.020 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.3162 | 13674.0 | 14413.7 | 2222.1 | -0.5 | 0.961 | 0.949 | 2.697 | HCC1806 QL-X-138 0 3 |
HCC1806 | QL-X-138 | 3 | 72 | 0.3162 | 13787.0 | 14413.7 | 2222.1 | -0.5 | 0.967 | 0.957 | 2.697 | HCC1806 QL-X-138 0 3 |