Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | Torin1 | 3 | 72 | 1.0 | 2247.0 | 6533.6 | 1943.1 | 0.0 | 0.087 | 0.344 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 1.0 | 2540.0 | 6533.6 | 1943.1 | 0.0 | 0.165 | 0.389 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 1.0 | 2417.0 | 6533.6 | 1943.1 | 0.0 | 0.133 | 0.370 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 1.0 | 2669.0 | 6533.6 | 1943.1 | 0.0 | 0.199 | 0.409 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 3.1623 | 2238.0 | 6533.6 | 1943.1 | 0.5 | 0.084 | 0.343 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 3.1623 | 1918.0 | 6533.6 | 1943.1 | 0.5 | -0.007 | 0.294 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 3.1623 | 2318.0 | 6533.6 | 1943.1 | 0.5 | 0.106 | 0.355 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 3.1623 | 2032.0 | 6533.6 | 1943.1 | 0.5 | 0.026 | 0.311 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 10.0 | 1596.0 | 6533.6 | 1943.1 | 1.0 | -0.106 | 0.244 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 10.0 | 1495.0 | 6533.6 | 1943.1 | 1.0 | -0.139 | 0.229 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 10.0 | 1483.0 | 6533.6 | 1943.1 | 1.0 | -0.143 | 0.227 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 10.0 | 1484.0 | 6533.6 | 1943.1 | 1.0 | -0.143 | 0.227 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin2 | 1 | 72 | 0.001 | 7244.0 | 7580.8 | 2503.8 | -3.0 | 0.944 | 0.956 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.001 | 6711.0 | 7580.8 | 2503.8 | -3.0 | 0.853 | 0.885 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.001 | 6449.0 | 7580.8 | 2503.8 | -3.0 | 0.808 | 0.851 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.001 | 6435.0 | 7580.8 | 2503.8 | -3.0 | 0.805 | 0.849 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0032 | 6216.0 | 7580.8 | 2503.8 | -2.49 | 0.766 | 0.820 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0032 | 5966.0 | 7580.8 | 2503.8 | -2.49 | 0.722 | 0.787 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0032 | 5842.0 | 7580.8 | 2503.8 | -2.49 | 0.699 | 0.771 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0032 | 6137.0 | 7580.8 | 2503.8 | -2.49 | 0.752 | 0.810 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.01 | 5027.0 | 7580.8 | 2503.8 | -2.0 | 0.547 | 0.663 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.01 | 4697.0 | 7580.8 | 2503.8 | -2.0 | 0.482 | 0.620 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.01 | 4789.0 | 7580.8 | 2503.8 | -2.0 | 0.500 | 0.632 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.01 | 5237.0 | 7580.8 | 2503.8 | -2.0 | 0.587 | 0.691 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0316 | 3519.0 | 7580.8 | 2503.8 | -1.5 | 0.237 | 0.464 | 1.598 | HCC70 Torin2 0 1 |