Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-XII-61 | 1 | 72 | 0.001 | 7865.0 | 7580.8 | 2503.8 | -3.0 | 1.050 | 1.040 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.0032 | 6944.0 | 7580.8 | 2503.8 | -2.49 | 0.893 | 0.916 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.0032 | 7290.0 | 7580.8 | 2503.8 | -2.49 | 0.952 | 0.962 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.0032 | 6991.0 | 7580.8 | 2503.8 | -2.49 | 0.901 | 0.922 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.0032 | 8524.0 | 7580.8 | 2503.8 | -2.49 | 1.150 | 1.120 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.01 | 7857.0 | 7580.8 | 2503.8 | -2.0 | 1.050 | 1.040 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.01 | 7277.0 | 7580.8 | 2503.8 | -2.0 | 0.949 | 0.960 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.01 | 8357.0 | 7580.8 | 2503.8 | -2.0 | 1.130 | 1.100 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.01 | 7772.0 | 7580.8 | 2503.8 | -2.0 | 1.030 | 1.030 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.0316 | 7285.0 | 7580.8 | 2503.8 | -1.5 | 0.951 | 0.961 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.0316 | 7092.0 | 7580.8 | 2503.8 | -1.5 | 0.918 | 0.936 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.0316 | 7862.0 | 7580.8 | 2503.8 | -1.5 | 1.050 | 1.040 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.0316 | 7762.0 | 7580.8 | 2503.8 | -1.5 | 1.030 | 1.020 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.1 | 7217.0 | 7580.8 | 2503.8 | -1.0 | 0.939 | 0.952 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.1 | 7552.0 | 7580.8 | 2503.8 | -1.0 | 0.995 | 0.996 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.1 | 7198.0 | 7580.8 | 2503.8 | -1.0 | 0.936 | 0.950 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.1 | 7565.0 | 7580.8 | 2503.8 | -1.0 | 0.997 | 0.998 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.3162 | 7096.0 | 7580.8 | 2503.8 | -0.5 | 0.919 | 0.936 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.3162 | 7215.0 | 7580.8 | 2503.8 | -0.5 | 0.939 | 0.952 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.3162 | 7664.0 | 7580.8 | 2503.8 | -0.5 | 1.010 | 1.010 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.3162 | 8065.0 | 7580.8 | 2503.8 | -0.5 | 1.080 | 1.060 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 1.0 | 7409.0 | 7580.8 | 2503.8 | 0.0 | 0.972 | 0.977 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 1.0 | 6932.0 | 7580.8 | 2503.8 | 0.0 | 0.891 | 0.914 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 1.0 | 7318.0 | 7580.8 | 2503.8 | 0.0 | 0.956 | 0.965 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 1.0 | 7965.0 | 7580.8 | 2503.8 | 0.0 | 1.060 | 1.050 | 1.598 | HCC70 QL-XII-61 0 1 |