Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)

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Cell line Drug name Experimental replicate Timepoint Drug concentration Live cell count Average live cell count, DMSO control Average live cell count (time = 0) Log10(drug concentration) GR value Relative cell count (treatment versus DMSO) Cell doublings (DMSO control) Experiment name
HCC1806 Torin2 1 72
3.1623
 1160.0 17793.8 2895.7
0.5
 -0.295 0.065 2.619
HCC1806 Torin2 0 1
HCC1806 Torin2 1 72
10.0
 526.0 17793.8 2895.7
1.0
 -0.479 0.030 2.619
HCC1806 Torin2 0 1
HCC1806 Torin2 1 72
10.0
 688.0 17793.8 2895.7
1.0
 -0.422 0.039 2.619
HCC1806 Torin2 0 1
HCC1806 Torin2 1 72
10.0
 675.0 17793.8 2895.7
1.0
 -0.426 0.038 2.619
HCC1806 Torin2 0 1
HCC1806 Torin2 1 72
10.0
 779.0 17793.8 2895.7
1.0
 -0.394 0.044 2.619
HCC1806 Torin2 0 1
HCC1806 Torin2 2 72
0.001
 19421.0 18525.7 2822.7
-3.0
 1.040 1.050 2.714
HCC1806 Torin2 0 2
HCC1806 Torin2 2 72
0.001
 18331.0 18525.7 2822.7
-3.0
 0.992 0.989 2.714
HCC1806 Torin2 0 2
HCC1806 Torin2 2 72
0.001
 18418.0 18525.7 2822.7
-3.0
 0.996 0.994 2.714
HCC1806 Torin2 0 2
HCC1806 Torin2 2 72
0.001
 17524.0 18525.7 2822.7
-3.0
 0.959 0.946 2.714
HCC1806 Torin2 0 2
HCC1806 Torin2 2 72
0.0032
 18497.0 18525.7 2822.7
-2.49
 0.999 0.998 2.714
HCC1806 Torin2 0 2
HCC1806 Torin2 2 72
0.0032
 18545.0 18525.7 2822.7
-2.49
 1.000 1.000 2.714
HCC1806 Torin2 0 2
HCC1806 Torin2 2 72
0.0032
 17009.0 18525.7 2822.7
-2.49
 0.938 0.918 2.714
HCC1806 Torin2 0 2
HCC1806 Torin2 2 72
0.0032
 17783.0 18525.7 2822.7
-2.49
 0.970 0.960 2.714
HCC1806 Torin2 0 2
HCC1806 Torin2 2 72
0.01
 15804.0 18525.7 2822.7
-2.0
 0.886 0.853 2.714
HCC1806 Torin2 0 2
HCC1806 Torin2 2 72
0.01
 16879.0 18525.7 2822.7
-2.0
 0.933 0.911 2.714
HCC1806 Torin2 0 2
HCC1806 Torin2 2 72
0.01
 16981.0 18525.7 2822.7
-2.0
 0.937 0.917 2.714
HCC1806 Torin2 0 2
HCC1806 Torin2 2 72
0.01
 16501.0 18525.7 2822.7
-2.0
 0.917 0.891 2.714
HCC1806 Torin2 0 2
HCC1806 Torin2 2 72
0.0316
 12478.0 18525.7 2822.7
-1.5
 0.729 0.674 2.714
HCC1806 Torin2 0 2
HCC1806 Torin2 2 72
0.0316
 12738.0 18525.7 2822.7
-1.5
 0.742 0.688 2.714
HCC1806 Torin2 0 2
HCC1806 Torin2 2 72
0.0316
 11579.0 18525.7 2822.7
-1.5
 0.682 0.625 2.714
HCC1806 Torin2 0 2
HCC1806 Torin2 2 72
0.0316
 12637.0 18525.7 2822.7
-1.5
 0.737 0.682 2.714
HCC1806 Torin2 0 2
HCC1806 Torin2 2 72
0.1
 7809.0 18525.7 2822.7
-1.0
 0.455 0.422 2.714
HCC1806 Torin2 0 2
HCC1806 Torin2 2 72
0.1
 7578.0 18525.7 2822.7
-1.0
 0.439 0.409 2.714
HCC1806 Torin2 0 2
HCC1806 Torin2 2 72
0.1
 7977.0 18525.7 2822.7
-1.0
 0.466 0.431 2.714
HCC1806 Torin2 0 2
HCC1806 Torin2 2 72
0.1
 8328.0 18525.7 2822.7
-1.0
 0.490 0.450 2.714
HCC1806 Torin2 0 2