Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-IV-100 | 3 | 72 | 0.1 | 4151.0 | 6533.6 | 1943.1 | -1.0 | 0.543 | 0.635 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.1 | 4339.0 | 6533.6 | 1943.1 | -1.0 | 0.583 | 0.664 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.1 | 3895.0 | 6533.6 | 1943.1 | -1.0 | 0.488 | 0.596 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.1 | 3729.0 | 6533.6 | 1943.1 | -1.0 | 0.451 | 0.571 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.0316 | 5720.0 | 6533.6 | 1943.1 | -1.5 | 0.854 | 0.875 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.0316 | 5382.0 | 6533.6 | 1943.1 | -1.5 | 0.790 | 0.824 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.0316 | 5356.0 | 6533.6 | 1943.1 | -1.5 | 0.785 | 0.820 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.0316 | 4970.0 | 6533.6 | 1943.1 | -1.5 | 0.711 | 0.761 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.01 | 6577.0 | 6533.6 | 1943.1 | -2.0 | 1.010 | 1.010 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.01 | 5379.0 | 6533.6 | 1943.1 | -2.0 | 0.790 | 0.823 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.01 | 5870.0 | 6533.6 | 1943.1 | -2.0 | 0.881 | 0.898 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.01 | 5854.0 | 6533.6 | 1943.1 | -2.0 | 0.878 | 0.896 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.0032 | 6495.0 | 6533.6 | 1943.1 | -2.49 | 0.993 | 0.994 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.0032 | 6943.0 | 6533.6 | 1943.1 | -2.49 | 1.070 | 1.060 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.0032 | 6490.0 | 6533.6 | 1943.1 | -2.49 | 0.992 | 0.993 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.0032 | 6389.0 | 6533.6 | 1943.1 | -2.49 | 0.975 | 0.978 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.001 | 6013.0 | 6533.6 | 1943.1 | -3.0 | 0.907 | 0.920 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.001 | 6226.0 | 6533.6 | 1943.1 | -3.0 | 0.946 | 0.953 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.001 | 6601.0 | 6533.6 | 1943.1 | -3.0 | 1.010 | 1.010 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.001 | 6490.0 | 6533.6 | 1943.1 | -3.0 | 0.992 | 0.993 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 2 | 72 | 10.0 | 259.0 | 7167.9 | 2409.0 | 1.0 | -0.758 | 0.036 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 10.0 | 275.0 | 7167.9 | 2409.0 | 1.0 | -0.748 | 0.038 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 10.0 | 289.0 | 7167.9 | 2409.0 | 1.0 | -0.740 | 0.040 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 10.0 | 269.0 | 7167.9 | 2409.0 | 1.0 | -0.752 | 0.038 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 3.1623 | 585.0 | 7167.9 | 2409.0 | 0.5 | -0.593 | 0.082 | 1.573 | HCC70 QL-IV-100 0 2 |