Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-V-107 | 1 | 72 | 10.0 | 596.0 | 7580.8 | 2503.8 | 1.0 | -0.593 | 0.079 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.0032 | 16843.0 | 17793.8 | 2895.7 | -2.49 | 0.959 | 0.947 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 10.0 | 555.0 | 7580.8 | 2503.8 | 1.0 | -0.610 | 0.073 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.0316 | 6973.0 | 7580.8 | 2503.8 | -1.5 | 0.898 | 0.920 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.1 | 4909.0 | 7580.8 | 2503.8 | -1.0 | 0.524 | 0.648 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.01 | 16696.0 | 17793.8 | 2895.7 | -2.0 | 0.952 | 0.938 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.1 | 5099.0 | 7580.8 | 2503.8 | -1.0 | 0.561 | 0.673 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.0316 | 7509.0 | 7580.8 | 2503.8 | -1.5 | 0.988 | 0.991 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.0316 | 6667.0 | 7580.8 | 2503.8 | -1.5 | 0.846 | 0.879 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.0316 | 6742.0 | 7580.8 | 2503.8 | -1.5 | 0.859 | 0.889 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.1 | 4657.0 | 7580.8 | 2503.8 | -1.0 | 0.474 | 0.614 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.0032 | 7768.0 | 7580.8 | 2503.8 | -2.49 | 1.030 | 1.020 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 3.1623 | 3011.0 | 7580.8 | 2503.8 | 0.5 | 0.122 | 0.397 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.01 | 6661.0 | 7580.8 | 2503.8 | -2.0 | 0.845 | 0.879 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.3162 | 3727.0 | 7580.8 | 2503.8 | -0.5 | 0.283 | 0.492 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.001 | 7499.0 | 7580.8 | 2503.8 | -3.0 | 0.986 | 0.989 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.001 | 6963.0 | 7580.8 | 2503.8 | -3.0 | 0.896 | 0.919 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.001 | 7362.0 | 7580.8 | 2503.8 | -3.0 | 0.964 | 0.971 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.3162 | 3706.0 | 7580.8 | 2503.8 | -0.5 | 0.278 | 0.489 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.0032 | 7694.0 | 7580.8 | 2503.8 | -2.49 | 1.020 | 1.010 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.0316 | 4744.0 | 7580.8 | 2503.8 | -1.5 | 0.492 | 0.626 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.0032 | 7562.0 | 7580.8 | 2503.8 | -2.49 | 0.997 | 0.998 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.3162 | 3705.0 | 7580.8 | 2503.8 | -0.5 | 0.278 | 0.489 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.3162 | 11390.0 | 17793.8 | 2895.7 | -0.5 | 0.687 | 0.640 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.3162 | 11620.0 | 17793.8 | 2895.7 | -0.5 | 0.700 | 0.653 | 2.619 | HCC1806 QL-V-107 0 1 |