Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-VIII-58 | 2 | 72 | 3.1623 | 48.0 | 7167.9 | 2409.0 | 0.5 | -0.917 | 0.007 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 10.0 | 146.0 | 18525.7 | 2822.7 | 1.0 | -0.664 | 0.008 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 3.1623 | 59.0 | 7167.9 | 2409.0 | 0.5 | -0.905 | 0.008 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 1 | 72 | 3.1623 | 64.0 | 7580.8 | 2503.8 | 0.5 | -0.899 | 0.008 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 10.0 | 147.0 | 18525.7 | 2822.7 | 1.0 | -0.663 | 0.008 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 1 | 72 | 3.1623 | 61.0 | 7580.8 | 2503.8 | 0.5 | -0.902 | 0.008 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 10.0 | 154.0 | 17793.8 | 2895.7 | 1.0 | -0.674 | 0.009 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 10.0 | 155.0 | 17793.8 | 2895.7 | 1.0 | -0.673 | 0.009 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 10.0 | 181.0 | 17793.8 | 2895.7 | 1.0 | -0.653 | 0.010 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 10.0 | 219.0 | 17793.8 | 2895.7 | 1.0 | -0.627 | 0.012 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 10.0 | 237.0 | 17793.8 | 2895.7 | 1.0 | -0.615 | 0.013 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 2 | 72 | 10.0 | 258.0 | 18525.7 | 2822.7 | 1.0 | -0.586 | 0.014 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC70 | QL-VIII-58 | 3 | 72 | 3.1623 | 98.0 | 6533.6 | 1943.1 | 0.5 | -0.819 | 0.015 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-XII-47 | 1 | 72 | 10.0 | 113.0 | 7580.8 | 2503.8 | 1.0 | -0.856 | 0.015 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-VIII-58 | 3 | 72 | 3.1623 | 96.0 | 6533.6 | 1943.1 | 0.5 | -0.821 | 0.015 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 10.0 | 222.0 | 14413.7 | 2222.1 | 1.0 | -0.574 | 0.015 | 2.697 | HCC1806 Torin2 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 3.1623 | 98.0 | 6533.6 | 1943.1 | 0.5 | -0.819 | 0.015 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC1806 | QL-XII-47 | 1 | 72 | 10.0 | 280.0 | 17793.8 | 2895.7 | 1.0 | -0.590 | 0.016 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | Torin2 | 3 | 72 | 10.0 | 234.0 | 14413.7 | 2222.1 | 1.0 | -0.566 | 0.016 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 10.0 | 236.0 | 14413.7 | 2222.1 | 1.0 | -0.565 | 0.016 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | QL-XII-47 | 1 | 72 | 10.0 | 309.0 | 17793.8 | 2895.7 | 1.0 | -0.574 | 0.017 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC70 | QL-VIII-58 | 3 | 72 | 3.1623 | 116.0 | 6533.6 | 1943.1 | 0.5 | -0.800 | 0.018 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC1806 | QL-XII-47 | 2 | 72 | 10.0 | 340.0 | 18525.7 | 2822.7 | 1.0 | -0.541 | 0.018 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | Torin2 | 3 | 72 | 10.0 | 253.0 | 14413.7 | 2222.1 | 1.0 | -0.553 | 0.018 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | QL-XII-47 | 2 | 72 | 10.0 | 348.0 | 18525.7 | 2822.7 | 1.0 | -0.538 | 0.019 | 2.714 | HCC1806 QL-XII-47 0 2 |