Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-V-107 | 3 | 72 | 3.1623 | 584.0 | 6533.6 | 1943.1 | 0.5 | -0.497 | 0.089 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 3.1623 | 582.0 | 6533.6 | 1943.1 | 0.5 | -0.498 | 0.089 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC1806 | QL-V-73 | 3 | 72 | 10.0 | 1275.0 | 14413.7 | 2222.1 | 1.0 | -0.186 | 0.089 | 2.697 | HCC1806 QL-V-73 0 3 |
| HCC70 | QL-IV-100 | 1 | 72 | 3.1623 | 686.0 | 7580.8 | 2503.8 | 0.5 | -0.555 | 0.091 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 3.1623 | 699.0 | 7580.8 | 2503.8 | 0.5 | -0.550 | 0.092 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-V-107 | 2 | 72 | 3.1623 | 658.0 | 7167.9 | 2409.0 | 0.5 | -0.562 | 0.092 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC1806 | QL-VI-86 | 1 | 72 | 10.0 | 1659.0 | 17793.8 | 2895.7 | 1.0 | -0.192 | 0.093 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC1806 | QL-V-73 | 1 | 72 | 10.0 | 1652.0 | 17793.8 | 2895.7 | 1.0 | -0.193 | 0.093 | 2.619 | HCC1806 QL-V-73 0 1 |
| HCC70 | QL-V-73 | 1 | 72 | 10.0 | 703.0 | 7580.8 | 2503.8 | 1.0 | -0.548 | 0.093 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC1806 | QL-V-107 | 3 | 72 | 3.1623 | 1375.0 | 14413.7 | 2222.1 | 0.5 | -0.163 | 0.095 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 3.1623 | 622.0 | 6533.6 | 1943.1 | 0.5 | -0.479 | 0.095 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 3.1623 | 620.0 | 6533.6 | 1943.1 | 0.5 | -0.479 | 0.095 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 2 | 72 | 3.1623 | 680.0 | 7167.9 | 2409.0 | 0.5 | -0.552 | 0.095 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC1806 | Torin2 | 1 | 72 | 0.3162 | 1684.0 | 17793.8 | 2895.7 | -0.5 | -0.187 | 0.095 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | QL-V-73 | 3 | 72 | 10.0 | 1376.0 | 14413.7 | 2222.1 | 1.0 | -0.163 | 0.096 | 2.697 | HCC1806 QL-V-73 0 3 |
| HCC1806 | QL-V-73 | 2 | 72 | 10.0 | 1789.0 | 18525.7 | 2822.7 | 1.0 | -0.155 | 0.097 | 2.714 | HCC1806 QL-V-73 0 2 |
| HCC1806 | QL-V-73 | 1 | 72 | 10.0 | 1728.0 | 17793.8 | 2895.7 | 1.0 | -0.179 | 0.097 | 2.619 | HCC1806 QL-V-73 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 3.1623 | 753.0 | 7580.8 | 2503.8 | 0.5 | -0.528 | 0.099 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 3.1623 | 1757.0 | 17793.8 | 2895.7 | 0.5 | -0.174 | 0.099 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 3.1623 | 1759.0 | 17793.8 | 2895.7 | 0.5 | -0.173 | 0.099 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC70 | QL-V-107 | 3 | 72 | 3.1623 | 648.0 | 6533.6 | 1943.1 | 0.5 | -0.466 | 0.099 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-73 | 1 | 72 | 10.0 | 753.0 | 7580.8 | 2503.8 | 1.0 | -0.528 | 0.099 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC1806 | QL-V-107 | 2 | 72 | 3.1623 | 1850.0 | 18525.7 | 2822.7 | 0.5 | -0.144 | 0.100 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 1 | 72 | 3.1623 | 767.0 | 7580.8 | 2503.8 | 0.5 | -0.523 | 0.101 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC1806 | QL-V-73 | 1 | 72 | 10.0 | 1792.0 | 17793.8 | 2895.7 | 1.0 | -0.167 | 0.101 | 2.619 | HCC1806 QL-V-73 0 1 |