Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-VI-86 | 1 | 72 | 10.0 | 1440.0 | 17793.8 | 2895.7 | 1.0 | -0.234 | 0.081 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC70 | QL-V-73 | 2 | 72 | 10.0 | 583.0 | 7167.9 | 2409.0 | 1.0 | -0.594 | 0.081 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC1806 | QL-V-107 | 3 | 72 | 3.1623 | 1161.0 | 14413.7 | 2222.1 | 0.5 | -0.214 | 0.081 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 3.1623 | 536.0 | 6533.6 | 1943.1 | 0.5 | -0.521 | 0.082 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 10.0 | 537.0 | 6533.6 | 1943.1 | 1.0 | -0.521 | 0.082 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-IV-100 | 2 | 72 | 3.1623 | 585.0 | 7167.9 | 2409.0 | 0.5 | -0.593 | 0.082 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-V-73 | 1 | 72 | 10.0 | 619.0 | 7580.8 | 2503.8 | 1.0 | -0.583 | 0.082 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC1806 | QL-V-73 | 3 | 72 | 10.0 | 1176.0 | 14413.7 | 2222.1 | 1.0 | -0.210 | 0.082 | 2.697 | HCC1806 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 2 | 72 | 10.0 | 586.0 | 7167.9 | 2409.0 | 1.0 | -0.593 | 0.082 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-IV-100 | 3 | 72 | 3.1623 | 544.0 | 6533.6 | 1943.1 | 0.5 | -0.517 | 0.083 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 3.1623 | 540.0 | 6533.6 | 1943.1 | 0.5 | -0.519 | 0.083 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 10.0 | 547.0 | 6533.6 | 1943.1 | 1.0 | -0.515 | 0.084 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-XII-47 | 1 | 72 | 3.1623 | 637.0 | 7580.8 | 2503.8 | 0.5 | -0.575 | 0.084 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | Torin2 | 2 | 72 | 0.3162 | 599.0 | 7167.9 | 2409.0 | -0.5 | -0.587 | 0.084 | 1.573 | HCC70 Torin2 0 2 |
| HCC1806 | QL-VI-86 | 3 | 72 | 10.0 | 1226.0 | 14413.7 | 2222.1 | 1.0 | -0.198 | 0.085 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC70 | QL-IV-100 | 1 | 72 | 3.1623 | 642.0 | 7580.8 | 2503.8 | 0.5 | -0.573 | 0.085 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 3.1623 | 641.0 | 7580.8 | 2503.8 | 0.5 | -0.574 | 0.085 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-V-73 | 3 | 72 | 10.0 | 554.0 | 6533.6 | 1943.1 | 1.0 | -0.512 | 0.085 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 1 | 72 | 10.0 | 647.0 | 7580.8 | 2503.8 | 1.0 | -0.571 | 0.085 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC1806 | QL-VI-86 | 1 | 72 | 10.0 | 1527.0 | 17793.8 | 2895.7 | 1.0 | -0.217 | 0.086 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC1806 | QL-V-107 | 3 | 72 | 3.1623 | 1251.0 | 14413.7 | 2222.1 | 0.5 | -0.192 | 0.087 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-VI-86 | 1 | 72 | 10.0 | 1541.0 | 17793.8 | 2895.7 | 1.0 | -0.214 | 0.087 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 3.1623 | 1544.0 | 17793.8 | 2895.7 | 0.5 | -0.213 | 0.087 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC70 | QL-V-107 | 2 | 72 | 3.1623 | 629.0 | 7167.9 | 2409.0 | 0.5 | -0.574 | 0.088 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC1806 | QL-V-107 | 1 | 72 | 3.1623 | 1573.0 | 17793.8 | 2895.7 | 0.5 | -0.208 | 0.088 | 2.619 | HCC1806 QL-V-107 0 1 |