Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-V-73 | 3 | 72 | 10.0 | 460.0 | 6533.6 | 1943.1 | 1.0 | -0.561 | 0.070 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-107 | 1 | 72 | 10.0 | 527.0 | 7580.8 | 2503.8 | 1.0 | -0.623 | 0.070 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC1806 | QL-IV-100 | 2 | 72 | 10.0 | 1288.0 | 18525.7 | 2822.7 | 1.0 | -0.251 | 0.070 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | QL-IV-100 | 1 | 72 | 10.0 | 1250.0 | 17793.8 | 2895.7 | 1.0 | -0.274 | 0.070 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-V-107 | 2 | 72 | 10.0 | 1297.0 | 18525.7 | 2822.7 | 1.0 | -0.249 | 0.070 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 10.0 | 502.0 | 7167.9 | 2409.0 | 1.0 | -0.631 | 0.070 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-IV-100 | 1 | 72 | 3.1623 | 529.0 | 7580.8 | 2503.8 | 0.5 | -0.622 | 0.070 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 3.1623 | 1264.0 | 17793.8 | 2895.7 | 0.5 | -0.271 | 0.071 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC70 | QL-V-73 | 2 | 72 | 10.0 | 511.0 | 7167.9 | 2409.0 | 1.0 | -0.627 | 0.071 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC1806 | QL-XII-47 | 1 | 72 | 3.1623 | 1281.0 | 17793.8 | 2895.7 | 0.5 | -0.268 | 0.072 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC70 | QL-IV-100 | 2 | 72 | 3.1623 | 518.0 | 7167.9 | 2409.0 | 0.5 | -0.624 | 0.072 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC1806 | QL-IV-100 | 1 | 72 | 10.0 | 1289.0 | 17793.8 | 2895.7 | 1.0 | -0.266 | 0.072 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-VI-86 | 3 | 72 | 10.0 | 1049.0 | 14413.7 | 2222.1 | 1.0 | -0.243 | 0.073 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC70 | QL-XII-47 | 2 | 72 | 3.1623 | 526.0 | 7167.9 | 2409.0 | 0.5 | -0.620 | 0.073 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | QL-V-107 | 1 | 72 | 10.0 | 555.0 | 7580.8 | 2503.8 | 1.0 | -0.610 | 0.073 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC1806 | QL-VI-86 | 3 | 72 | 10.0 | 1071.0 | 14413.7 | 2222.1 | 1.0 | -0.237 | 0.074 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC70 | QL-IV-100 | 1 | 72 | 3.1623 | 561.0 | 7580.8 | 2503.8 | 0.5 | -0.608 | 0.074 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC1806 | QL-VI-86 | 3 | 72 | 10.0 | 1068.0 | 14413.7 | 2222.1 | 1.0 | -0.238 | 0.074 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC1806 | QL-IV-100 | 1 | 72 | 3.1623 | 1369.0 | 17793.8 | 2895.7 | 0.5 | -0.249 | 0.077 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-V-73 | 3 | 72 | 10.0 | 1102.0 | 14413.7 | 2222.1 | 1.0 | -0.229 | 0.077 | 2.697 | HCC1806 QL-V-73 0 3 |
| HCC70 | QL-V-107 | 2 | 72 | 3.1623 | 558.0 | 7167.9 | 2409.0 | 0.5 | -0.605 | 0.078 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC1806 | QL-IV-100 | 1 | 72 | 10.0 | 1392.0 | 17793.8 | 2895.7 | 1.0 | -0.244 | 0.078 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 3.1623 | 1411.0 | 17793.8 | 2895.7 | 0.5 | -0.240 | 0.079 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 10.0 | 596.0 | 7580.8 | 2503.8 | 1.0 | -0.593 | 0.079 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-IV-100 | 2 | 72 | 3.1623 | 566.0 | 7167.9 | 2409.0 | 0.5 | -0.602 | 0.079 | 1.573 | HCC70 QL-IV-100 0 2 |