Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-XII-61 | 3 | 72 | 0.3162 | 14282.0 | 14413.7 | 2222.1 | -0.5 | 0.993 | 0.991 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.3162 | 15657.0 | 14413.7 | 2222.1 | -0.5 | 1.060 | 1.090 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-V-73 | 3 | 72 | 0.3162 | 14592.0 | 14413.7 | 2222.1 | -0.5 | 1.010 | 1.010 | 2.697 | HCC1806 QL-V-73 0 3 |
| HCC1806 | QL-V-73 | 2 | 72 | 0.3162 | 16778.0 | 18525.7 | 2822.7 | -0.5 | 0.928 | 0.906 | 2.714 | HCC1806 QL-V-73 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.3162 | 599.0 | 7167.9 | 2409.0 | -0.5 | -0.587 | 0.084 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | QL-X-138 | 1 | 72 | 0.3162 | 7053.0 | 7580.8 | 2503.8 | -0.5 | 0.912 | 0.930 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC1806 | QL-V-73 | 2 | 72 | 0.3162 | 17685.0 | 18525.7 | 2822.7 | -0.5 | 0.966 | 0.955 | 2.714 | HCC1806 QL-V-73 0 2 |
| HCC70 | QL-X-138 | 1 | 72 | 0.3162 | 6600.0 | 7580.8 | 2503.8 | -0.5 | 0.834 | 0.871 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC1806 | QL-V-73 | 2 | 72 | 0.3162 | 18158.0 | 18525.7 | 2822.7 | -0.5 | 0.985 | 0.980 | 2.714 | HCC1806 QL-V-73 0 2 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.3162 | 5938.0 | 6533.6 | 1943.1 | -0.5 | 0.894 | 0.909 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | Torin2 | 2 | 72 | 0.3162 | 942.0 | 7167.9 | 2409.0 | -0.5 | -0.449 | 0.131 | 1.573 | HCC70 Torin2 0 2 |
| HCC1806 | QL-V-73 | 2 | 72 | 0.3162 | 17222.0 | 18525.7 | 2822.7 | -0.5 | 0.947 | 0.930 | 2.714 | HCC1806 QL-V-73 0 2 |
| HCC1806 | QL-V-73 | 3 | 72 | 0.3162 | 12980.0 | 14413.7 | 2222.1 | -0.5 | 0.924 | 0.901 | 2.697 | HCC1806 QL-V-73 0 3 |
| HCC70 | QL-V-107 | 2 | 72 | 0.3162 | 2843.0 | 7167.9 | 2409.0 | -0.5 | 0.111 | 0.397 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.3162 | 7096.0 | 7580.8 | 2503.8 | -0.5 | 0.919 | 0.936 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-V-107 | 2 | 72 | 0.3162 | 3247.0 | 7167.9 | 2409.0 | -0.5 | 0.209 | 0.453 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 0.3162 | 2862.0 | 7167.9 | 2409.0 | -0.5 | 0.116 | 0.399 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.3162 | 793.0 | 7167.9 | 2409.0 | -0.5 | -0.507 | 0.111 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 0.3162 | 3095.0 | 7167.9 | 2409.0 | -0.5 | 0.173 | 0.432 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.3162 | 925.0 | 7167.9 | 2409.0 | -0.5 | -0.456 | 0.129 | 1.573 | HCC70 Torin2 0 2 |
| HCC1806 | QL-V-73 | 3 | 72 | 0.3162 | 12501.0 | 14413.7 | 2222.1 | -0.5 | 0.897 | 0.867 | 2.697 | HCC1806 QL-V-73 0 3 |
| HCC70 | Torin2 | 1 | 72 | 0.3162 | 848.0 | 7580.8 | 2503.8 | -0.5 | -0.492 | 0.112 | 1.598 | HCC70 Torin2 0 1 |
| HCC1806 | QL-V-73 | 1 | 72 | 0.3162 | 16556.0 | 17793.8 | 2895.7 | -0.5 | 0.946 | 0.930 | 2.619 | HCC1806 QL-V-73 0 1 |
| HCC1806 | QL-V-73 | 1 | 72 | 0.3162 | 16374.0 | 17793.8 | 2895.7 | -0.5 | 0.938 | 0.920 | 2.619 | HCC1806 QL-V-73 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.3162 | 3920.0 | 7580.8 | 2503.8 | -0.5 | 0.324 | 0.517 | 1.598 | HCC70 QL-IV-100 0 1 |