Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | AZD8055 | 2 | 72 | 1.0 | 2573.0 | 7167.9 | 2409.0 | 0.0 | 0.043 | 0.359 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-XII-108 | 2 | 72 | 1.0 | 5190.0 | 7167.9 | 2409.0 | 0.0 | 0.629 | 0.724 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC1806 | Torin1 | 2 | 72 | 1.0 | 7733.0 | 18525.7 | 2822.7 | 0.0 | 0.450 | 0.417 | 2.714 | HCC1806 Torin1 0 2 |
| HCC1806 | Torin1 | 2 | 72 | 1.0 | 8413.0 | 18525.7 | 2822.7 | 0.0 | 0.495 | 0.454 | 2.714 | HCC1806 Torin1 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 1.0 | 2987.0 | 7167.9 | 2409.0 | 0.0 | 0.146 | 0.417 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-VI-86 | 3 | 72 | 1.0 | 2628.0 | 6533.6 | 1943.1 | 0.0 | 0.188 | 0.402 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 1.0 | 3420.0 | 6533.6 | 1943.1 | 0.0 | 0.381 | 0.523 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-XII-47 | 1 | 72 | 1.0 | 3819.0 | 7580.8 | 2503.8 | 0.0 | 0.302 | 0.504 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-X-138 | 1 | 72 | 1.0 | 4926.0 | 7580.8 | 2503.8 | 0.0 | 0.527 | 0.650 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | Torin2 | 2 | 72 | 1.0 | 209.0 | 7167.9 | 2409.0 | 0.0 | -0.789 | 0.029 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | QL-V-107 | 3 | 72 | 1.0 | 1363.0 | 6533.6 | 1943.1 | 0.0 | -0.183 | 0.209 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | Torin2 | 2 | 72 | 1.0 | 241.0 | 7167.9 | 2409.0 | 0.0 | -0.769 | 0.034 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | QL-XII-108 | 3 | 72 | 1.0 | 4089.0 | 6533.6 | 1943.1 | 0.0 | 0.530 | 0.626 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | Torin2 | 3 | 72 | 1.0 | 284.0 | 6533.6 | 1943.1 | 0.0 | -0.667 | 0.044 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | QL-IV-100 | 1 | 72 | 1.0 | 1611.0 | 7580.8 | 2503.8 | 0.0 | -0.241 | 0.213 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 1.0 | 7466.0 | 17793.8 | 2895.7 | 0.0 | 0.436 | 0.420 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 1.0 | 1630.0 | 7580.8 | 2503.8 | 0.0 | -0.236 | 0.215 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-XII-108 | 3 | 72 | 1.0 | 4650.0 | 6533.6 | 1943.1 | 0.0 | 0.647 | 0.712 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-IV-100 | 1 | 72 | 1.0 | 1549.0 | 7580.8 | 2503.8 | 0.0 | -0.260 | 0.204 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC1806 | AZD8055 | 2 | 72 | 1.0 | 8501.0 | 18525.7 | 2822.7 | 0.0 | 0.501 | 0.459 | 2.714 | HCC1806 AZD8055 0 2 |
| HCC70 | QL-IV-100 | 1 | 72 | 1.0 | 1415.0 | 7580.8 | 2503.8 | 0.0 | -0.300 | 0.187 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-V-107 | 3 | 72 | 1.0 | 1481.0 | 6533.6 | 1943.1 | 0.0 | -0.144 | 0.227 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 1.0 | 3478.0 | 6533.6 | 1943.1 | 0.0 | 0.395 | 0.532 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC1806 | Torin2 | 1 | 72 | 1.0 | 1059.0 | 17793.8 | 2895.7 | 0.0 | -0.319 | 0.060 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | Torin2 | 1 | 72 | 1.0 | 1119.0 | 17793.8 | 2895.7 | 0.0 | -0.304 | 0.063 | 2.619 | HCC1806 Torin2 0 1 |