Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-XII-108 | 1 | 72 | 3.1623 | 12330.0 | 17793.8 | 2895.7 | 0.5 | 0.739 | 0.693 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 3.1623 | 12866.0 | 17793.8 | 2895.7 | 0.5 | 0.767 | 0.723 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC70 | QL-VI-86 | 2 | 72 | 3.1623 | 788.0 | 7167.9 | 2409.0 | 0.5 | -0.509 | 0.110 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-VI-86 | 2 | 72 | 3.1623 | 870.0 | 7167.9 | 2409.0 | 0.5 | -0.477 | 0.121 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-VI-86 | 2 | 72 | 3.1623 | 862.0 | 7167.9 | 2409.0 | 0.5 | -0.480 | 0.120 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-VI-86 | 2 | 72 | 3.1623 | 841.0 | 7167.9 | 2409.0 | 0.5 | -0.488 | 0.117 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-XII-47 | 1 | 72 | 3.1623 | 641.0 | 7580.8 | 2503.8 | 0.5 | -0.574 | 0.085 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 3.1623 | 637.0 | 7580.8 | 2503.8 | 0.5 | -0.575 | 0.084 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC1806 | Torin2 | 3 | 72 | 3.1623 | 899.0 | 14413.7 | 2222.1 | 0.5 | -0.285 | 0.062 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 3.1623 | 847.0 | 14413.7 | 2222.1 | 0.5 | -0.301 | 0.059 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 3.1623 | 881.0 | 14413.7 | 2222.1 | 0.5 | -0.290 | 0.061 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 3.1623 | 821.0 | 14413.7 | 2222.1 | 0.5 | -0.309 | 0.057 | 2.697 | HCC1806 Torin2 0 3 |
| HCC70 | Torin2 | 2 | 72 | 3.1623 | 28.0 | 7167.9 | 2409.0 | 0.5 | -0.941 | 0.004 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 3.1623 | 17.0 | 7167.9 | 2409.0 | 0.5 | -0.957 | 0.002 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 3.1623 | 25.0 | 7167.9 | 2409.0 | 0.5 | -0.945 | 0.003 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 3.1623 | 26.0 | 7167.9 | 2409.0 | 0.5 | -0.944 | 0.004 | 1.573 | HCC70 Torin2 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 3.1623 | 12258.0 | 18525.7 | 2822.7 | 0.5 | 0.718 | 0.662 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 3.1623 | 10872.0 | 18525.7 | 2822.7 | 0.5 | 0.643 | 0.587 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 3.1623 | 12037.0 | 18525.7 | 2822.7 | 0.5 | 0.706 | 0.650 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 3.1623 | 12690.0 | 18525.7 | 2822.7 | 0.5 | 0.740 | 0.685 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC70 | QL-VI-86 | 1 | 72 | 3.1623 | 1012.0 | 7580.8 | 2503.8 | 0.5 | -0.433 | 0.133 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 3.1623 | 1011.0 | 7580.8 | 2503.8 | 0.5 | -0.433 | 0.133 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 3.1623 | 1062.0 | 7580.8 | 2503.8 | 0.5 | -0.415 | 0.140 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 3.1623 | 1014.0 | 7580.8 | 2503.8 | 0.5 | -0.432 | 0.134 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC1806 | QL-V-73 | 1 | 72 | 3.1623 | 6477.0 | 17793.8 | 2895.7 | 0.5 | 0.360 | 0.364 | 2.619 | HCC1806 QL-V-73 0 1 |