Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-IV-100 | 2 | 72 | 0.001 | 6268.0 | 7167.9 | 2409.0 | -3.0 | 0.837 | 0.874 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.001 | 7088.0 | 7580.8 | 2503.8 | -3.0 | 0.918 | 0.935 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-V-107 | 3 | 72 | 0.001 | 6629.0 | 6533.6 | 1943.1 | -3.0 | 1.020 | 1.010 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.001 | 6456.0 | 6533.6 | 1943.1 | -3.0 | 0.986 | 0.988 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | AZD8055 | 2 | 72 | 0.001 | 6736.0 | 7167.9 | 2409.0 | -3.0 | 0.923 | 0.940 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.001 | 6963.0 | 7580.8 | 2503.8 | -3.0 | 0.896 | 0.919 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-V-107 | 3 | 72 | 0.001 | 6565.0 | 6533.6 | 1943.1 | -3.0 | 1.010 | 1.000 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.001 | 7489.0 | 7580.8 | 2503.8 | -3.0 | 0.985 | 0.988 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.001 | 6454.0 | 7167.9 | 2409.0 | -3.0 | 0.871 | 0.900 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | AZD8055 | 3 | 72 | 0.001 | 6096.0 | 6533.6 | 1943.1 | -3.0 | 0.922 | 0.933 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.001 | 7425.0 | 7167.9 | 2409.0 | -3.0 | 1.050 | 1.040 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.001 | 6675.0 | 6533.6 | 1943.1 | -3.0 | 1.020 | 1.020 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | AZD8055 | 1 | 72 | 0.001 | 7324.0 | 7580.8 | 2503.8 | -3.0 | 0.957 | 0.966 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.001 | 7090.0 | 7580.8 | 2503.8 | -3.0 | 0.918 | 0.935 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.001 | 6750.0 | 7167.9 | 2409.0 | -3.0 | 0.925 | 0.942 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | AZD8055 | 3 | 72 | 0.001 | 6302.0 | 6533.6 | 1943.1 | -3.0 | 0.959 | 0.965 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-V-107 | 1 | 72 | 0.001 | 7047.0 | 7580.8 | 2503.8 | -3.0 | 0.911 | 0.930 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | AZD8055 | 2 | 72 | 0.001 | 6624.0 | 7167.9 | 2409.0 | -3.0 | 0.902 | 0.924 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-V-107 | 1 | 72 | 0.001 | 7243.0 | 7580.8 | 2503.8 | -3.0 | 0.944 | 0.955 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 0.001 | 6680.0 | 7580.8 | 2503.8 | -3.0 | 0.848 | 0.881 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.001 | 6645.0 | 7580.8 | 2503.8 | -3.0 | 0.842 | 0.877 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 3 | 72 | 0.001 | 6136.0 | 6533.6 | 1943.1 | -3.0 | 0.929 | 0.939 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.001 | 6026.0 | 6533.6 | 1943.1 | -3.0 | 0.910 | 0.922 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-X-138 | 1 | 72 | 0.001 | 7346.0 | 7580.8 | 2503.8 | -3.0 | 0.961 | 0.969 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | QL-X-138 | 1 | 72 | 0.001 | 7447.0 | 7580.8 | 2503.8 | -3.0 | 0.978 | 0.982 | 1.598 | HCC70 QL-X-138 0 1 |