Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-XII-61 | 1 | 72 | 0.0032 | 6944.0 | 7580.8 | 2503.8 | -2.49 | 0.893 | 0.916 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.0032 | 14904.0 | 14413.7 | 2222.1 | -2.49 | 1.020 | 1.030 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC70 | QL-X-138 | 2 | 72 | 0.0032 | 7303.0 | 7167.9 | 2409.0 | -2.49 | 1.020 | 1.020 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.0032 | 5346.0 | 7167.9 | 2409.0 | -2.49 | 0.660 | 0.746 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.0032 | 6819.0 | 7167.9 | 2409.0 | -2.49 | 0.938 | 0.951 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC1806 | QL-V-73 | 2 | 72 | 0.0032 | 18287.0 | 18525.7 | 2822.7 | -2.49 | 0.990 | 0.987 | 2.714 | HCC1806 QL-V-73 0 2 |
| HCC70 | QL-XII-108 | 2 | 72 | 0.0032 | 7674.0 | 7167.9 | 2409.0 | -2.49 | 1.090 | 1.070 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.0032 | 7121.0 | 7167.9 | 2409.0 | -2.49 | 0.992 | 0.993 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC1806 | QL-V-73 | 1 | 72 | 0.0032 | 17376.0 | 17793.8 | 2895.7 | -2.49 | 0.982 | 0.977 | 2.619 | HCC1806 QL-V-73 0 1 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.0032 | 6119.0 | 6533.6 | 1943.1 | -2.49 | 0.926 | 0.937 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-XII-108 | 2 | 72 | 0.0032 | 6758.0 | 7167.9 | 2409.0 | -2.49 | 0.927 | 0.943 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.0032 | 7844.0 | 7167.9 | 2409.0 | -2.49 | 1.120 | 1.090 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.0032 | 5558.0 | 7167.9 | 2409.0 | -2.49 | 0.701 | 0.775 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | QL-XII-108 | 2 | 72 | 0.0032 | 7290.0 | 7167.9 | 2409.0 | -2.49 | 1.020 | 1.020 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC70 | AZD8055 | 1 | 72 | 0.0032 | 7768.0 | 7580.8 | 2503.8 | -2.49 | 1.030 | 1.020 | 1.598 | HCC70 AZD8055 0 1 |
| HCC1806 | QL-V-73 | 1 | 72 | 0.0032 | 16970.0 | 17793.8 | 2895.7 | -2.49 | 0.964 | 0.954 | 2.619 | HCC1806 QL-V-73 0 1 |
| HCC1806 | QL-V-73 | 2 | 72 | 0.0032 | 18189.0 | 18525.7 | 2822.7 | -2.49 | 0.987 | 0.982 | 2.714 | HCC1806 QL-V-73 0 2 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.0032 | 6417.0 | 6533.6 | 1943.1 | -2.49 | 0.980 | 0.982 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.0032 | 6784.0 | 6533.6 | 1943.1 | -2.49 | 1.040 | 1.040 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | Torin2 | 1 | 72 | 0.0032 | 6216.0 | 7580.8 | 2503.8 | -2.49 | 0.766 | 0.820 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0032 | 5842.0 | 7580.8 | 2503.8 | -2.49 | 0.699 | 0.771 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0032 | 6137.0 | 7580.8 | 2503.8 | -2.49 | 0.752 | 0.810 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0032 | 5966.0 | 7580.8 | 2503.8 | -2.49 | 0.722 | 0.787 | 1.598 | HCC70 Torin2 0 1 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.0032 | 14351.0 | 14413.7 | 2222.1 | -2.49 | 0.997 | 0.996 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-V-73 | 1 | 72 | 0.0032 | 17142.0 | 17793.8 | 2895.7 | -2.49 | 0.972 | 0.963 | 2.619 | HCC1806 QL-V-73 0 1 |