Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-V-73 | 1 | 72 | 0.001 | 8034.0 | 7580.8 | 2503.8 | -3.0 | 1.070 | 1.060 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC70 | QL-V-73 | 2 | 72 | 0.001 | 6280.0 | 7167.9 | 2409.0 | -3.0 | 0.839 | 0.876 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-V-73 | 2 | 72 | 0.001 | 6894.0 | 7167.9 | 2409.0 | -3.0 | 0.951 | 0.962 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.001 | 6226.0 | 6533.6 | 1943.1 | -3.0 | 0.946 | 0.953 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.001 | 6478.0 | 6533.6 | 1943.1 | -3.0 | 0.990 | 0.991 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | AZD8055 | 1 | 72 | 0.001 | 7324.0 | 7580.8 | 2503.8 | -3.0 | 0.957 | 0.966 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 3 | 72 | 0.001 | 6096.0 | 6533.6 | 1943.1 | -3.0 | 0.922 | 0.933 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.001 | 6750.0 | 7167.9 | 2409.0 | -3.0 | 0.925 | 0.942 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.001 | 7090.0 | 7580.8 | 2503.8 | -3.0 | 0.918 | 0.935 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.001 | 6645.0 | 7580.8 | 2503.8 | -3.0 | 0.842 | 0.877 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 2 | 72 | 0.001 | 6736.0 | 7167.9 | 2409.0 | -3.0 | 0.923 | 0.940 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.001 | 6624.0 | 7167.9 | 2409.0 | -3.0 | 0.902 | 0.924 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.001 | 6048.0 | 7167.9 | 2409.0 | -3.0 | 0.795 | 0.844 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.001 | 6775.0 | 7167.9 | 2409.0 | -3.0 | 0.930 | 0.945 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 1 | 72 | 0.001 | 6611.0 | 7580.8 | 2503.8 | -3.0 | 0.836 | 0.872 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 3 | 72 | 0.001 | 6026.0 | 6533.6 | 1943.1 | -3.0 | 0.910 | 0.922 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.001 | 6490.0 | 6533.6 | 1943.1 | -3.0 | 0.992 | 0.993 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.001 | 6454.0 | 7167.9 | 2409.0 | -3.0 | 0.871 | 0.900 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-V-107 | 1 | 72 | 0.001 | 7047.0 | 7580.8 | 2503.8 | -3.0 | 0.911 | 0.930 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-V-107 | 2 | 72 | 0.001 | 6157.0 | 7167.9 | 2409.0 | -3.0 | 0.816 | 0.859 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 0.001 | 6808.0 | 7167.9 | 2409.0 | -3.0 | 0.936 | 0.950 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | AZD8055 | 1 | 72 | 0.001 | 6827.0 | 7580.8 | 2503.8 | -3.0 | 0.873 | 0.901 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 3 | 72 | 0.001 | 6302.0 | 6533.6 | 1943.1 | -3.0 | 0.959 | 0.965 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.001 | 7181.0 | 7580.8 | 2503.8 | -3.0 | 0.933 | 0.947 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.001 | 7695.0 | 7580.8 | 2503.8 | -3.0 | 1.020 | 1.020 | 1.598 | HCC70 QL-VI-86 0 1 |