Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-XII-47 | 3 | 72 | 0.001 | 6411.0 | 6533.6 | 1943.1 | -3.0 | 0.978 | 0.981 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC1806 | QL-IV-100 | 2 | 72 | 0.001 | 18295.0 | 18525.7 | 2822.7 | -3.0 | 0.991 | 0.988 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 0.001 | 18083.0 | 18525.7 | 2822.7 | -3.0 | 0.982 | 0.976 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC70 | QL-X-138 | 3 | 72 | 0.001 | 5733.0 | 6533.6 | 1943.1 | -3.0 | 0.856 | 0.877 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.001 | 6478.0 | 6533.6 | 1943.1 | -3.0 | 0.990 | 0.991 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-VI-86 | 2 | 72 | 0.001 | 6779.0 | 7167.9 | 2409.0 | -3.0 | 0.930 | 0.946 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.001 | 7560.0 | 7580.8 | 2503.8 | -3.0 | 0.997 | 0.997 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-X-138 | 3 | 72 | 0.001 | 6154.0 | 6533.6 | 1943.1 | -3.0 | 0.933 | 0.942 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.001 | 5853.0 | 6533.6 | 1943.1 | -3.0 | 0.878 | 0.896 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-X-138 | 1 | 72 | 0.0032 | 7491.0 | 7580.8 | 2503.8 | -2.49 | 0.985 | 0.988 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.0032 | 6844.0 | 7580.8 | 2503.8 | -2.49 | 0.876 | 0.903 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-X-138 | 1 | 72 | 0.0032 | 7514.0 | 7580.8 | 2503.8 | -2.49 | 0.989 | 0.991 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.0032 | 8198.0 | 7580.8 | 2503.8 | -2.49 | 1.100 | 1.080 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-V-73 | 1 | 72 | 0.0032 | 7503.0 | 7580.8 | 2503.8 | -2.49 | 0.987 | 0.990 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.0032 | 7410.0 | 7580.8 | 2503.8 | -2.49 | 0.972 | 0.977 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.0032 | 8343.0 | 7580.8 | 2503.8 | -2.49 | 1.120 | 1.100 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-X-138 | 1 | 72 | 0.0032 | 8144.0 | 7580.8 | 2503.8 | -2.49 | 1.090 | 1.070 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.0032 | 7700.0 | 7580.8 | 2503.8 | -2.49 | 1.020 | 1.020 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.0032 | 7741.0 | 7580.8 | 2503.8 | -2.49 | 1.030 | 1.020 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.0032 | 17965.0 | 17793.8 | 2895.7 | -2.49 | 1.010 | 1.010 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.0032 | 18684.0 | 17793.8 | 2895.7 | -2.49 | 1.040 | 1.050 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC70 | QL-V-73 | 1 | 72 | 0.0032 | 7575.0 | 7580.8 | 2503.8 | -2.49 | 0.999 | 0.999 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.0032 | 16634.0 | 17793.8 | 2895.7 | -2.49 | 0.949 | 0.935 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC70 | QL-V-73 | 1 | 72 | 0.0032 | 7250.0 | 7580.8 | 2503.8 | -2.49 | 0.945 | 0.956 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.0032 | 7424.0 | 7580.8 | 2503.8 | -2.49 | 0.974 | 0.979 | 1.598 | HCC70 QL-VI-86 0 1 |