Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | Torin1 | 2 | 72 | 0.001 | 17557.0 | 18525.7 | 2822.7 | -3.0 | 0.961 | 0.948 | 2.714 | HCC1806 Torin1 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 0.001 | 6646.0 | 7167.9 | 2409.0 | -3.0 | 0.906 | 0.927 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 0.001 | 6157.0 | 7167.9 | 2409.0 | -3.0 | 0.816 | 0.859 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 0.001 | 6808.0 | 7167.9 | 2409.0 | -3.0 | 0.936 | 0.950 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 0.001 | 7123.0 | 7167.9 | 2409.0 | -3.0 | 0.992 | 0.994 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | AZD8055 | 1 | 72 | 0.001 | 7324.0 | 7580.8 | 2503.8 | -3.0 | 0.957 | 0.966 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-V-107 | 3 | 72 | 0.001 | 6565.0 | 6533.6 | 1943.1 | -3.0 | 1.010 | 1.000 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-XII-47 | 2 | 72 | 0.001 | 7469.0 | 7167.9 | 2409.0 | -3.0 | 1.050 | 1.040 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.001 | 6489.0 | 7167.9 | 2409.0 | -3.0 | 0.877 | 0.905 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 3 | 72 | 0.001 | 6199.0 | 6533.6 | 1943.1 | -3.0 | 0.941 | 0.949 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | QL-V-73 | 2 | 72 | 0.001 | 6883.0 | 7167.9 | 2409.0 | -3.0 | 0.949 | 0.960 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-X-138 | 1 | 72 | 0.001 | 7346.0 | 7580.8 | 2503.8 | -3.0 | 0.961 | 0.969 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.001 | 6070.0 | 6533.6 | 1943.1 | -3.0 | 0.918 | 0.929 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.001 | 5682.0 | 6533.6 | 1943.1 | -3.0 | 0.847 | 0.870 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-V-73 | 1 | 72 | 0.001 | 7308.0 | 7580.8 | 2503.8 | -3.0 | 0.955 | 0.964 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.001 | 7490.0 | 7580.8 | 2503.8 | -3.0 | 0.985 | 0.988 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.001 | 6022.0 | 6533.6 | 1943.1 | -3.0 | 0.909 | 0.922 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.001 | 6326.0 | 6533.6 | 1943.1 | -3.0 | 0.963 | 0.968 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.001 | 6483.0 | 6533.6 | 1943.1 | -3.0 | 0.991 | 0.992 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC1806 | AZD8055 | 1 | 72 | 0.001 | 17216.0 | 17793.8 | 2895.7 | -3.0 | 0.975 | 0.968 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.001 | 7422.0 | 7580.8 | 2503.8 | -3.0 | 0.974 | 0.979 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-V-73 | 2 | 72 | 0.001 | 6280.0 | 7167.9 | 2409.0 | -3.0 | 0.839 | 0.876 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.001 | 6456.0 | 6533.6 | 1943.1 | -3.0 | 0.986 | 0.988 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC1806 | Torin2 | 1 | 72 | 0.001 | 17714.0 | 17793.8 | 2895.7 | -3.0 | 0.997 | 0.996 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | Torin2 | 1 | 72 | 0.001 | 17283.0 | 17793.8 | 2895.7 | -3.0 | 0.978 | 0.971 | 2.619 | HCC1806 Torin2 0 1 |