Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-X-138 | 2 | 72 | 0.001 | 7670.0 | 7167.9 | 2409.0 | -3.0 | 1.090 | 1.070 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.001 | 7256.0 | 7167.9 | 2409.0 | -3.0 | 1.020 | 1.010 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC1806 | QL-X-138 | 3 | 72 | 0.001 | 14349.0 | 14413.7 | 2222.1 | -3.0 | 0.997 | 0.996 | 2.697 | HCC1806 QL-X-138 0 3 |
| HCC1806 | QL-X-138 | 3 | 72 | 0.001 | 13694.0 | 14413.7 | 2222.1 | -3.0 | 0.962 | 0.950 | 2.697 | HCC1806 QL-X-138 0 3 |
| HCC1806 | QL-X-138 | 3 | 72 | 0.001 | 14679.0 | 14413.7 | 2222.1 | -3.0 | 1.010 | 1.020 | 2.697 | HCC1806 QL-X-138 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.001 | 5976.0 | 6533.6 | 1943.1 | -3.0 | 0.901 | 0.915 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-X-138 | 2 | 72 | 0.001 | 8440.0 | 7167.9 | 2409.0 | -3.0 | 1.220 | 1.180 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.001 | 6297.0 | 6533.6 | 1943.1 | -3.0 | 0.958 | 0.964 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.001 | 17924.0 | 18525.7 | 2822.7 | -3.0 | 0.976 | 0.968 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.001 | 6843.0 | 6533.6 | 1943.1 | -3.0 | 1.050 | 1.050 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.001 | 19628.0 | 18525.7 | 2822.7 | -3.0 | 1.040 | 1.060 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.001 | 6699.0 | 6533.6 | 1943.1 | -3.0 | 1.030 | 1.030 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.001 | 13709.0 | 14413.7 | 2222.1 | -3.0 | 0.963 | 0.951 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.001 | 7362.0 | 7580.8 | 2503.8 | -3.0 | 0.964 | 0.971 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-V-73 | 2 | 72 | 0.001 | 6280.0 | 7167.9 | 2409.0 | -3.0 | 0.839 | 0.876 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.001 | 7422.0 | 7580.8 | 2503.8 | -3.0 | 0.974 | 0.979 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-X-138 | 3 | 72 | 0.001 | 6144.0 | 6533.6 | 1943.1 | -3.0 | 0.931 | 0.940 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.001 | 7231.0 | 7580.8 | 2503.8 | -3.0 | 0.942 | 0.954 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-V-73 | 2 | 72 | 0.001 | 6883.0 | 7167.9 | 2409.0 | -3.0 | 0.949 | 0.960 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.001 | 7181.0 | 7580.8 | 2503.8 | -3.0 | 0.933 | 0.947 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.001 | 7695.0 | 7580.8 | 2503.8 | -3.0 | 1.020 | 1.020 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-X-138 | 3 | 72 | 0.001 | 6942.0 | 6533.6 | 1943.1 | -3.0 | 1.070 | 1.060 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-V-73 | 2 | 72 | 0.001 | 7041.0 | 7167.9 | 2409.0 | -3.0 | 0.977 | 0.982 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.001 | 17153.0 | 17793.8 | 2895.7 | -3.0 | 0.972 | 0.964 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.001 | 18181.0 | 17793.8 | 2895.7 | -3.0 | 1.020 | 1.020 | 2.619 | HCC1806 QL-XII-61 0 1 |