Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | Torin2 | 2 | 72 | 0.0032 | 6063.0 | 7167.9 | 2409.0 | -2.49 | 0.798 | 0.846 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.01 | 4457.0 | 7167.9 | 2409.0 | -2.0 | 0.479 | 0.622 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.01 | 4295.0 | 7167.9 | 2409.0 | -2.0 | 0.444 | 0.599 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.01 | 4787.0 | 7167.9 | 2409.0 | -2.0 | 0.547 | 0.668 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.01 | 4609.0 | 7167.9 | 2409.0 | -2.0 | 0.510 | 0.643 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.0316 | 3416.0 | 7167.9 | 2409.0 | -1.5 | 0.249 | 0.477 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.0316 | 3534.0 | 7167.9 | 2409.0 | -1.5 | 0.276 | 0.493 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.0316 | 3436.0 | 7167.9 | 2409.0 | -1.5 | 0.253 | 0.479 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.0316 | 3343.0 | 7167.9 | 2409.0 | -1.5 | 0.232 | 0.466 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.1 | 2153.0 | 7167.9 | 2409.0 | -1.0 | -0.069 | 0.300 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.1 | 2178.0 | 7167.9 | 2409.0 | -1.0 | -0.062 | 0.304 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.1 | 2232.0 | 7167.9 | 2409.0 | -1.0 | -0.047 | 0.311 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.1 | 2438.0 | 7167.9 | 2409.0 | -1.0 | 0.008 | 0.340 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.3162 | 793.0 | 7167.9 | 2409.0 | -0.5 | -0.507 | 0.111 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.3162 | 599.0 | 7167.9 | 2409.0 | -0.5 | -0.587 | 0.084 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.3162 | 942.0 | 7167.9 | 2409.0 | -0.5 | -0.449 | 0.131 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.3162 | 925.0 | 7167.9 | 2409.0 | -0.5 | -0.456 | 0.129 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 1.0 | 233.0 | 7167.9 | 2409.0 | 0.0 | -0.773 | 0.033 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 1.0 | 209.0 | 7167.9 | 2409.0 | 0.0 | -0.789 | 0.029 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 1.0 | 178.0 | 7167.9 | 2409.0 | 0.0 | -0.809 | 0.025 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 1.0 | 241.0 | 7167.9 | 2409.0 | 0.0 | -0.769 | 0.034 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 3.1623 | 26.0 | 7167.9 | 2409.0 | 0.5 | -0.944 | 0.004 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 3.1623 | 25.0 | 7167.9 | 2409.0 | 0.5 | -0.945 | 0.003 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 3.1623 | 17.0 | 7167.9 | 2409.0 | 0.5 | -0.957 | 0.002 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 3.1623 | 28.0 | 7167.9 | 2409.0 | 0.5 | -0.941 | 0.004 | 1.573 | HCC70 Torin2 0 2 |