Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-IV-100 | 3 | 72 | 0.0316 | 13822.0 | 14413.7 | 2222.1 | -1.5 | 0.969 | 0.959 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 0.1 | 10978.0 | 14413.7 | 2222.1 | -1.0 | 0.808 | 0.762 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 0.1 | 11000.0 | 14413.7 | 2222.1 | -1.0 | 0.809 | 0.763 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 0.3162 | 6777.0 | 14413.7 | 2222.1 | -0.5 | 0.512 | 0.470 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 0.3162 | 6482.0 | 14413.7 | 2222.1 | -0.5 | 0.487 | 0.450 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 1.0 | 1591.0 | 14413.7 | 2222.1 | 0.0 | -0.116 | 0.110 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 1.0 | 1622.0 | 14413.7 | 2222.1 | 0.0 | -0.110 | 0.113 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 3.1623 | 934.0 | 14413.7 | 2222.1 | 0.5 | -0.275 | 0.065 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 3.1623 | 805.0 | 14413.7 | 2222.1 | 0.5 | -0.314 | 0.056 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 10.0 | 810.0 | 14413.7 | 2222.1 | 1.0 | -0.312 | 0.056 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 10.0 | 975.0 | 14413.7 | 2222.1 | 1.0 | -0.263 | 0.068 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.001 | 17376.0 | 17793.8 | 2895.7 | -3.0 | 0.982 | 0.977 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.001 | 16430.0 | 17793.8 | 2895.7 | -3.0 | 0.940 | 0.923 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.0032 | 16878.0 | 17793.8 | 2895.7 | -2.49 | 0.960 | 0.949 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.0032 | 16747.0 | 17793.8 | 2895.7 | -2.49 | 0.954 | 0.941 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.01 | 16696.0 | 17793.8 | 2895.7 | -2.0 | 0.952 | 0.938 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.01 | 16853.0 | 17793.8 | 2895.7 | -2.0 | 0.959 | 0.947 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.0316 | 16000.0 | 17793.8 | 2895.7 | -1.5 | 0.920 | 0.899 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.0316 | 16597.0 | 17793.8 | 2895.7 | -1.5 | 0.948 | 0.933 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.1 | 15098.0 | 17793.8 | 2895.7 | -1.0 | 0.878 | 0.849 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.1 | 14821.0 | 17793.8 | 2895.7 | -1.0 | 0.865 | 0.833 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.3162 | 11390.0 | 17793.8 | 2895.7 | -0.5 | 0.687 | 0.640 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.3162 | 11128.0 | 17793.8 | 2895.7 | -0.5 | 0.672 | 0.625 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 10.0 | 1071.0 | 17793.8 | 2895.7 | 1.0 | -0.316 | 0.060 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 10.0 | 1018.0 | 17793.8 | 2895.7 | 1.0 | -0.329 | 0.057 | 2.619 | HCC1806 QL-V-107 0 1 |