Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | AZD8055 | 3 | 72 | 1.0 | 2573.0 | 6533.6 | 1943.1 | 0.0 | 0.174 | 0.394 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 3.1623 | 2571.0 | 6533.6 | 1943.1 | 0.5 | 0.174 | 0.394 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 1.0 | 2950.0 | 6533.6 | 1943.1 | 0.0 | 0.270 | 0.452 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 1.0 | 1205.0 | 6533.6 | 1943.1 | 0.0 | -0.239 | 0.184 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 3.1623 | 2477.0 | 6533.6 | 1943.1 | 0.5 | 0.149 | 0.379 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 10.0 | 2318.0 | 6533.6 | 1943.1 | 1.0 | 0.106 | 0.355 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 3.1623 | 2446.0 | 6533.6 | 1943.1 | 0.5 | 0.141 | 0.374 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 3.1623 | 540.0 | 6533.6 | 1943.1 | 0.5 | -0.519 | 0.083 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 10.0 | 2127.0 | 6533.6 | 1943.1 | 1.0 | 0.053 | 0.326 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 10.0 | 2011.0 | 6533.6 | 1943.1 | 1.0 | 0.020 | 0.308 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 10.0 | 2061.0 | 6533.6 | 1943.1 | 1.0 | 0.034 | 0.315 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 10.0 | 313.0 | 6533.6 | 1943.1 | 1.0 | -0.648 | 0.048 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.001 | 6302.0 | 6533.6 | 1943.1 | -3.0 | 0.959 | 0.965 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.0032 | 6102.0 | 6533.6 | 1943.1 | -2.49 | 0.923 | 0.934 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.0032 | 6520.0 | 6533.6 | 1943.1 | -2.49 | 0.998 | 0.998 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.0316 | 3966.0 | 6533.6 | 1943.1 | -1.5 | 0.504 | 0.607 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.0032 | 5579.0 | 6533.6 | 1943.1 | -2.49 | 0.827 | 0.854 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.01 | 5184.0 | 6533.6 | 1943.1 | -2.0 | 0.752 | 0.793 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.0032 | 6391.0 | 6533.6 | 1943.1 | -2.49 | 0.975 | 0.978 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.001 | 6601.0 | 6533.6 | 1943.1 | -3.0 | 1.010 | 1.010 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.01 | 5390.0 | 6533.6 | 1943.1 | -2.0 | 0.792 | 0.825 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.001 | 6136.0 | 6533.6 | 1943.1 | -3.0 | 0.929 | 0.939 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.001 | 6026.0 | 6533.6 | 1943.1 | -3.0 | 0.910 | 0.922 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 0.001 | 6194.0 | 6533.6 | 1943.1 | -3.0 | 0.940 | 0.948 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 0.001 | 6159.0 | 6533.6 | 1943.1 | -3.0 | 0.934 | 0.943 | 1.750 | HCC70 QL-V-107 0 3 |