Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-V-107 | 3 | 72 | 0.001 | 14579.0 | 14413.7 | 2222.1 | -3.0 | 1.010 | 1.010 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.0032 | 14218.0 | 14413.7 | 2222.1 | -2.49 | 0.990 | 0.986 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.01 | 15287.0 | 14413.7 | 2222.1 | -2.0 | 1.040 | 1.060 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.0316 | 11618.0 | 14413.7 | 2222.1 | -1.5 | 0.846 | 0.806 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.0316 | 10919.0 | 14413.7 | 2222.1 | -1.5 | 0.804 | 0.758 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.1 | 9250.0 | 14413.7 | 2222.1 | -1.0 | 0.697 | 0.642 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.01 | 14217.0 | 14413.7 | 2222.1 | -2.0 | 0.990 | 0.986 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.01 | 13559.0 | 14413.7 | 2222.1 | -2.0 | 0.955 | 0.941 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.01 | 13818.0 | 14413.7 | 2222.1 | -2.0 | 0.969 | 0.959 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.01 | 13170.0 | 14413.7 | 2222.1 | -2.0 | 0.934 | 0.914 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.1 | 7962.0 | 14413.7 | 2222.1 | -1.0 | 0.605 | 0.552 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 1.0 | 5758.0 | 14413.7 | 2222.1 | 0.0 | 0.423 | 0.399 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 0.001 | 14537.0 | 14413.7 | 2222.1 | -3.0 | 1.010 | 1.010 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.1 | 13008.0 | 14413.7 | 2222.1 | -1.0 | 0.925 | 0.902 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.1 | 11928.0 | 14413.7 | 2222.1 | -1.0 | 0.864 | 0.828 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.0032 | 14009.0 | 14413.7 | 2222.1 | -2.49 | 0.979 | 0.972 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.0032 | 13632.0 | 14413.7 | 2222.1 | -2.49 | 0.959 | 0.946 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.0032 | 13915.0 | 14413.7 | 2222.1 | -2.49 | 0.974 | 0.965 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.0032 | 14863.0 | 14413.7 | 2222.1 | -2.49 | 1.020 | 1.030 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.001 | 14500.0 | 14413.7 | 2222.1 | -3.0 | 1.000 | 1.010 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.001 | 14547.0 | 14413.7 | 2222.1 | -3.0 | 1.010 | 1.010 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.001 | 14590.0 | 14413.7 | 2222.1 | -3.0 | 1.010 | 1.010 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 0.001 | 14117.0 | 14413.7 | 2222.1 | -3.0 | 0.985 | 0.979 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.3162 | 8084.0 | 14413.7 | 2222.1 | -0.5 | 0.614 | 0.561 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.3162 | 8680.0 | 14413.7 | 2222.1 | -0.5 | 0.657 | 0.602 | 2.697 | HCC1806 QL-V-107 0 3 |