Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-V-73 | 3 | 72 | 0.0316 | 6027.0 | 6533.6 | 1943.1 | -1.5 | 0.910 | 0.922 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.1 | 5936.0 | 6533.6 | 1943.1 | -1.0 | 0.893 | 0.909 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.1 | 5539.0 | 6533.6 | 1943.1 | -1.0 | 0.820 | 0.848 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.0316 | 6239.0 | 6533.6 | 1943.1 | -1.5 | 0.948 | 0.955 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 0.01 | 6250.0 | 6533.6 | 1943.1 | -2.0 | 0.950 | 0.957 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 0.0316 | 5839.0 | 6533.6 | 1943.1 | -1.5 | 0.876 | 0.894 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.3162 | 4952.0 | 6533.6 | 1943.1 | -0.5 | 0.707 | 0.758 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.3162 | 5465.0 | 6533.6 | 1943.1 | -0.5 | 0.806 | 0.836 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 1.0 | 3478.0 | 6533.6 | 1943.1 | 0.0 | 0.395 | 0.532 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 1.0 | 3820.0 | 6533.6 | 1943.1 | 0.0 | 0.472 | 0.585 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 3.1623 | 1668.0 | 6533.6 | 1943.1 | 0.5 | -0.084 | 0.255 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 3.1623 | 1494.0 | 6533.6 | 1943.1 | 0.5 | -0.139 | 0.229 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 10.0 | 554.0 | 6533.6 | 1943.1 | 1.0 | -0.512 | 0.085 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 10.0 | 547.0 | 6533.6 | 1943.1 | 1.0 | -0.515 | 0.084 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.001 | 5929.0 | 6533.6 | 1943.1 | -3.0 | 0.892 | 0.907 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.001 | 6456.0 | 6533.6 | 1943.1 | -3.0 | 0.986 | 0.988 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.0032 | 6162.0 | 6533.6 | 1943.1 | -2.49 | 0.934 | 0.943 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.0032 | 6119.0 | 6533.6 | 1943.1 | -2.49 | 0.926 | 0.937 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.01 | 6570.0 | 6533.6 | 1943.1 | -2.0 | 1.010 | 1.010 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.01 | 6230.0 | 6533.6 | 1943.1 | -2.0 | 0.946 | 0.954 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 0.001 | 6194.0 | 6533.6 | 1943.1 | -3.0 | 0.940 | 0.948 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 0.01 | 6276.0 | 6533.6 | 1943.1 | -2.0 | 0.955 | 0.961 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.0316 | 5688.0 | 6533.6 | 1943.1 | -1.5 | 0.848 | 0.871 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.3162 | 5393.0 | 6533.6 | 1943.1 | -0.5 | 0.792 | 0.825 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.3162 | 5122.0 | 6533.6 | 1943.1 | -0.5 | 0.740 | 0.784 | 1.750 | HCC70 QL-XII-108 0 3 |