Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-V-107 | 3 | 72 | 0.3162 | 2933.0 | 6533.6 | 1943.1 | -0.5 | 0.265 | 0.449 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 1.0 | 1358.0 | 6533.6 | 1943.1 | 0.0 | -0.185 | 0.208 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 1.0 | 1363.0 | 6533.6 | 1943.1 | 0.0 | -0.183 | 0.209 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 1.0 | 1481.0 | 6533.6 | 1943.1 | 0.0 | -0.144 | 0.227 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 1.0 | 1241.0 | 6533.6 | 1943.1 | 0.0 | -0.226 | 0.190 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 10.0 | 393.0 | 6533.6 | 1943.1 | 1.0 | -0.599 | 0.060 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 3.1623 | 620.0 | 6533.6 | 1943.1 | 0.5 | -0.479 | 0.095 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 10.0 | 429.0 | 6533.6 | 1943.1 | 1.0 | -0.578 | 0.066 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-V-107 | 3 | 72 | 10.0 | 405.0 | 6533.6 | 1943.1 | 1.0 | -0.592 | 0.062 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 10.0 | 14.0 | 6533.6 | 1943.1 | 1.0 | -0.940 | 0.002 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 10.0 | 13.0 | 6533.6 | 1943.1 | 1.0 | -0.943 | 0.002 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 10.0 | 14.0 | 6533.6 | 1943.1 | 1.0 | -0.940 | 0.002 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.001 | 6154.0 | 6533.6 | 1943.1 | -3.0 | 0.933 | 0.942 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.0032 | 5733.0 | 6533.6 | 1943.1 | -2.49 | 0.856 | 0.877 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.0032 | 6894.0 | 6533.6 | 1943.1 | -2.49 | 1.060 | 1.060 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.01 | 6314.0 | 6533.6 | 1943.1 | -2.0 | 0.961 | 0.966 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.01 | 6445.0 | 6533.6 | 1943.1 | -2.0 | 0.984 | 0.986 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.0316 | 5677.0 | 6533.6 | 1943.1 | -1.5 | 0.846 | 0.869 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.0316 | 6788.0 | 6533.6 | 1943.1 | -1.5 | 1.040 | 1.040 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.0316 | 6826.0 | 6533.6 | 1943.1 | -1.5 | 1.050 | 1.040 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.1 | 5867.0 | 6533.6 | 1943.1 | -1.0 | 0.881 | 0.898 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.3162 | 5327.0 | 6533.6 | 1943.1 | -0.5 | 0.780 | 0.815 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.3162 | 4962.0 | 6533.6 | 1943.1 | -0.5 | 0.709 | 0.759 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 10.0 | 1242.0 | 6533.6 | 1943.1 | 1.0 | -0.226 | 0.190 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 10.0 | 1192.0 | 6533.6 | 1943.1 | 1.0 | -0.244 | 0.182 | 1.750 | HCC70 QL-X-138 0 3 |