Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-VI-86 | 2 | 72 | 10.0 | 337.0 | 7167.9 | 2409.0 | 1.0 | -0.714 | 0.047 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-VI-86 | 2 | 72 | 10.0 | 385.0 | 7167.9 | 2409.0 | 1.0 | -0.688 | 0.054 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-VI-86 | 2 | 72 | 10.0 | 383.0 | 7167.9 | 2409.0 | 1.0 | -0.689 | 0.053 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 1.0 | 4761.0 | 7167.9 | 2409.0 | 0.0 | 0.542 | 0.664 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 1.0 | 5252.0 | 7167.9 | 2409.0 | 0.0 | 0.641 | 0.733 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 3.1623 | 3355.0 | 7167.9 | 2409.0 | 0.5 | 0.234 | 0.468 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.3162 | 6117.0 | 7167.9 | 2409.0 | -0.5 | 0.808 | 0.853 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.3162 | 6147.0 | 7167.9 | 2409.0 | -0.5 | 0.814 | 0.858 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.3162 | 6696.0 | 7167.9 | 2409.0 | -0.5 | 0.915 | 0.934 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.1 | 7754.0 | 7167.9 | 2409.0 | -1.0 | 1.100 | 1.080 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.1 | 3166.0 | 7167.9 | 2409.0 | -1.0 | 0.190 | 0.442 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.1 | 6652.0 | 7167.9 | 2409.0 | -1.0 | 0.907 | 0.928 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.3162 | 7096.0 | 7167.9 | 2409.0 | -0.5 | 0.987 | 0.990 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 3.1623 | 3000.0 | 7167.9 | 2409.0 | 0.5 | 0.150 | 0.419 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-XII-108 | 2 | 72 | 0.1 | 7558.0 | 7167.9 | 2409.0 | -1.0 | 1.070 | 1.050 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.01 | 7762.0 | 7167.9 | 2409.0 | -2.0 | 1.100 | 1.080 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.01 | 7165.0 | 7167.9 | 2409.0 | -2.0 | 0.999 | 1.000 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.0316 | 7128.0 | 7167.9 | 2409.0 | -1.5 | 0.993 | 0.994 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.01 | 7456.0 | 7167.9 | 2409.0 | -2.0 | 1.050 | 1.040 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.0032 | 7303.0 | 7167.9 | 2409.0 | -2.49 | 1.020 | 1.020 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.01 | 7734.0 | 7167.9 | 2409.0 | -2.0 | 1.100 | 1.080 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.0316 | 8133.0 | 7167.9 | 2409.0 | -1.5 | 1.170 | 1.130 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.0032 | 6819.0 | 7167.9 | 2409.0 | -2.49 | 0.938 | 0.951 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.001 | 8440.0 | 7167.9 | 2409.0 | -3.0 | 1.220 | 1.180 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.0032 | 7121.0 | 7167.9 | 2409.0 | -2.49 | 0.992 | 0.993 | 1.573 | HCC70 QL-X-138 0 2 |