Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-XII-61 | 2 | 72 | 0.0316 | 17687.0 | 18525.7 | 2822.7 | -1.5 | 0.966 | 0.955 | 2.714 | HCC1806 QL-XII-61 0 2 |
| HCC1806 | QL-V-73 | 2 | 72 | 0.0316 | 17692.0 | 18525.7 | 2822.7 | -1.5 | 0.966 | 0.955 | 2.714 | HCC1806 QL-V-73 0 2 |
| HCC1806 | Torin2 | 1 | 72 | 0.001 | 17714.0 | 17793.8 | 2895.7 | -3.0 | 0.997 | 0.996 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.0032 | 17715.0 | 17793.8 | 2895.7 | -2.49 | 0.997 | 0.996 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | AZD8055 | 2 | 72 | 0.01 | 17722.0 | 18525.7 | 2822.7 | -2.0 | 0.968 | 0.957 | 2.714 | HCC1806 AZD8055 0 2 |
| HCC1806 | QL-X-138 | 2 | 72 | 0.3162 | 17727.0 | 18525.7 | 2822.7 | -0.5 | 0.968 | 0.957 | 2.714 | HCC1806 QL-X-138 0 2 |
| HCC1806 | QL-V-73 | 1 | 72 | 0.01 | 17746.0 | 17793.8 | 2895.7 | -2.0 | 0.998 | 0.997 | 2.619 | HCC1806 QL-V-73 0 1 |
| HCC1806 | QL-VI-86 | 1 | 72 | 0.001 | 17746.0 | 17793.8 | 2895.7 | -3.0 | 0.998 | 0.997 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC1806 | QL-VI-86 | 1 | 72 | 0.001 | 17755.0 | 17793.8 | 2895.7 | -3.0 | 0.998 | 0.998 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC1806 | QL-VI-86 | 1 | 72 | 0.1 | 17758.0 | 17793.8 | 2895.7 | -1.0 | 0.998 | 0.998 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC1806 | QL-X-138 | 1 | 72 | 0.3162 | 17764.0 | 17793.8 | 2895.7 | -0.5 | 0.999 | 0.998 | 2.619 | HCC1806 QL-X-138 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.0032 | 17765.0 | 17793.8 | 2895.7 | -2.49 | 0.999 | 0.998 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.0032 | 17768.0 | 18525.7 | 2822.7 | -2.49 | 0.969 | 0.959 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-108 | 1 | 72 | 0.01 | 17769.0 | 17793.8 | 2895.7 | -2.0 | 0.999 | 0.999 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | Torin2 | 2 | 72 | 0.0032 | 17783.0 | 18525.7 | 2822.7 | -2.49 | 0.970 | 0.960 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.0032 | 17784.0 | 17793.8 | 2895.7 | -2.49 | 1.000 | 0.999 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.001 | 17785.0 | 17793.8 | 2895.7 | -3.0 | 1.000 | 1.000 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.001 | 17790.0 | 17793.8 | 2895.7 | -3.0 | 1.000 | 1.000 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.0316 | 17803.0 | 18525.7 | 2822.7 | -1.5 | 0.971 | 0.961 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.01 | 17804.0 | 17793.8 | 2895.7 | -2.0 | 1.000 | 1.000 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-XII-61 | 2 | 72 | 0.0032 | 17807.0 | 18525.7 | 2822.7 | -2.49 | 0.971 | 0.961 | 2.714 | HCC1806 QL-XII-61 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.001 | 17811.0 | 18525.7 | 2822.7 | -3.0 | 0.971 | 0.961 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.001 | 17822.0 | 17793.8 | 2895.7 | -3.0 | 1.000 | 1.000 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-VI-86 | 1 | 72 | 0.001 | 17827.0 | 17793.8 | 2895.7 | -3.0 | 1.000 | 1.000 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC1806 | QL-V-107 | 2 | 72 | 0.0316 | 17828.0 | 18525.7 | 2822.7 | -1.5 | 0.972 | 0.962 | 2.714 | HCC1806 QL-V-107 0 2 |