Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | AZD8055 | 2 | 72 | 3.1623 | 2848.0 | 7167.9 | 2409.0 | 0.5 | 0.112 | 0.397 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | Torin1 | 3 | 72 | 0.3162 | 2849.0 | 6533.6 | 1943.1 | -0.5 | 0.245 | 0.436 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.3162 | 2859.0 | 6533.6 | 1943.1 | -0.5 | 0.247 | 0.438 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-V-107 | 2 | 72 | 0.3162 | 2862.0 | 7167.9 | 2409.0 | -0.5 | 0.116 | 0.399 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | Torin1 | 1 | 72 | 3.1623 | 2863.0 | 7580.8 | 2503.8 | 0.5 | 0.088 | 0.378 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 10.0 | 2870.0 | 7580.8 | 2503.8 | 1.0 | 0.089 | 0.379 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 10.0 | 2885.0 | 7580.8 | 2503.8 | 1.0 | 0.093 | 0.381 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 2 | 72 | 1.0 | 2886.0 | 7167.9 | 2409.0 | 0.0 | 0.122 | 0.403 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-VI-86 | 2 | 72 | 1.0 | 2887.0 | 7167.9 | 2409.0 | 0.0 | 0.122 | 0.403 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | Torin1 | 2 | 72 | 0.3162 | 2892.0 | 7167.9 | 2409.0 | -0.5 | 0.123 | 0.403 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | AZD8055 | 3 | 72 | 0.3162 | 2907.0 | 6533.6 | 1943.1 | -0.5 | 0.259 | 0.445 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | Torin1 | 2 | 72 | 0.3162 | 2919.0 | 7167.9 | 2409.0 | -0.5 | 0.130 | 0.407 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | QL-XII-108 | 1 | 72 | 10.0 | 2920.0 | 7580.8 | 2503.8 | 1.0 | 0.101 | 0.385 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.3162 | 2921.0 | 7167.9 | 2409.0 | -0.5 | 0.130 | 0.408 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.3162 | 2928.0 | 7167.9 | 2409.0 | -0.5 | 0.132 | 0.408 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-XII-47 | 2 | 72 | 1.0 | 2930.0 | 7167.9 | 2409.0 | 0.0 | 0.133 | 0.409 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | QL-V-107 | 3 | 72 | 0.3162 | 2933.0 | 6533.6 | 1943.1 | -0.5 | 0.265 | 0.449 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | Torin1 | 1 | 72 | 1.0 | 2938.0 | 7580.8 | 2503.8 | 0.0 | 0.105 | 0.388 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | AZD8055 | 3 | 72 | 1.0 | 2950.0 | 6533.6 | 1943.1 | 0.0 | 0.270 | 0.452 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-VI-86 | 1 | 72 | 1.0 | 2952.0 | 7580.8 | 2503.8 | 0.0 | 0.109 | 0.389 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.3162 | 2963.0 | 7167.9 | 2409.0 | -0.5 | 0.141 | 0.413 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.3162 | 2967.0 | 6533.6 | 1943.1 | -0.5 | 0.274 | 0.454 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | AZD8055 | 2 | 72 | 0.3162 | 2968.0 | 7167.9 | 2409.0 | -0.5 | 0.142 | 0.414 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 1 | 72 | 1.0 | 2978.0 | 7580.8 | 2503.8 | 0.0 | 0.115 | 0.393 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 2 | 72 | 1.0 | 2987.0 | 7167.9 | 2409.0 | 0.0 | 0.146 | 0.417 | 1.573 | HCC70 AZD8055 0 2 |