Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-IV-100 | 2 | 72 | 1.0 | 2669.0 | 18525.7 | 2822.7 | 0.0 | -0.020 | 0.144 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC70 | Torin1 | 3 | 72 | 1.0 | 2669.0 | 6533.6 | 1943.1 | 0.0 | 0.199 | 0.409 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.3162 | 2685.0 | 6533.6 | 1943.1 | -0.5 | 0.203 | 0.411 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | Torin1 | 1 | 72 | 3.1623 | 2686.0 | 7580.8 | 2503.8 | 0.5 | 0.045 | 0.354 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | QL-VI-86 | 3 | 72 | 1.0 | 2691.0 | 6533.6 | 1943.1 | 0.0 | 0.205 | 0.412 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.3162 | 2696.0 | 6533.6 | 1943.1 | -0.5 | 0.206 | 0.413 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.3162 | 2696.0 | 7167.9 | 2409.0 | -0.5 | 0.074 | 0.376 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-XII-108 | 2 | 72 | 10.0 | 2698.0 | 7167.9 | 2409.0 | 1.0 | 0.075 | 0.376 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC70 | Torin1 | 2 | 72 | 1.0 | 2714.0 | 7167.9 | 2409.0 | 0.0 | 0.079 | 0.379 | 1.573 | HCC70 Torin1 0 2 |
| HCC1806 | Torin1 | 3 | 72 | 10.0 | 2726.0 | 14413.7 | 2222.1 | 1.0 | 0.079 | 0.189 | 2.697 | HCC1806 Torin1 0 3 |
| HCC70 | QL-XII-108 | 2 | 72 | 10.0 | 2731.0 | 7167.9 | 2409.0 | 1.0 | 0.083 | 0.381 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC70 | Torin2 | 1 | 72 | 0.1 | 2732.0 | 7580.8 | 2503.8 | -1.0 | 0.056 | 0.360 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin1 | 3 | 72 | 0.3162 | 2735.0 | 6533.6 | 1943.1 | -0.5 | 0.216 | 0.419 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | QL-XII-108 | 1 | 72 | 10.0 | 2735.0 | 7580.8 | 2503.8 | 1.0 | 0.057 | 0.361 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.3162 | 2766.0 | 7167.9 | 2409.0 | -0.5 | 0.092 | 0.386 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-XII-108 | 1 | 72 | 10.0 | 2777.0 | 7580.8 | 2503.8 | 1.0 | 0.067 | 0.366 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 10.0 | 2785.0 | 7580.8 | 2503.8 | 1.0 | 0.069 | 0.367 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-V-107 | 3 | 72 | 0.3162 | 2787.0 | 6533.6 | 1943.1 | -0.5 | 0.229 | 0.427 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | AZD8055 | 1 | 72 | 10.0 | 2787.0 | 7580.8 | 2503.8 | 1.0 | 0.069 | 0.368 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 3 | 72 | 0.3162 | 2789.0 | 6533.6 | 1943.1 | -0.5 | 0.229 | 0.427 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.3162 | 2790.0 | 6533.6 | 1943.1 | -0.5 | 0.230 | 0.427 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | QL-XII-47 | 2 | 72 | 1.0 | 2812.0 | 7167.9 | 2409.0 | 0.0 | 0.103 | 0.392 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 3.1623 | 2831.0 | 7167.9 | 2409.0 | 0.5 | 0.108 | 0.395 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 3.1623 | 2838.0 | 7167.9 | 2409.0 | 0.5 | 0.110 | 0.396 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 0.3162 | 2843.0 | 7167.9 | 2409.0 | -0.5 | 0.111 | 0.397 | 1.573 | HCC70 QL-V-107 0 2 |