Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-VI-86 | 3 | 72 | 10.0 | 1226.0 | 14413.7 | 2222.1 | 1.0 | -0.198 | 0.085 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC1806 | QL-IV-100 | 2 | 72 | 3.1623 | 1229.0 | 18525.7 | 2822.7 | 0.5 | -0.264 | 0.066 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 3.1623 | 1231.0 | 18525.7 | 2822.7 | 0.5 | -0.263 | 0.066 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | Torin2 | 1 | 72 | 3.1623 | 1239.0 | 17793.8 | 2895.7 | 0.5 | -0.277 | 0.070 | 2.619 | HCC1806 Torin2 0 1 |
| HCC70 | QL-V-107 | 3 | 72 | 1.0 | 1241.0 | 6533.6 | 1943.1 | 0.0 | -0.226 | 0.190 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 10.0 | 1242.0 | 6533.6 | 1943.1 | 1.0 | -0.226 | 0.190 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-VIII-58 | 2 | 72 | 1.0 | 1243.0 | 7167.9 | 2409.0 | 0.0 | -0.343 | 0.173 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC1806 | QL-IV-100 | 1 | 72 | 10.0 | 1250.0 | 17793.8 | 2895.7 | 1.0 | -0.274 | 0.070 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 2 | 72 | 3.1623 | 1251.0 | 18525.7 | 2822.7 | 0.5 | -0.259 | 0.068 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | QL-V-107 | 3 | 72 | 3.1623 | 1251.0 | 14413.7 | 2222.1 | 0.5 | -0.192 | 0.087 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-XII-47 | 1 | 72 | 3.1623 | 1264.0 | 17793.8 | 2895.7 | 0.5 | -0.271 | 0.071 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | Torin2 | 2 | 72 | 3.1623 | 1264.0 | 18525.7 | 2822.7 | 0.5 | -0.256 | 0.068 | 2.714 | HCC1806 Torin2 0 2 |
| HCC70 | QL-VIII-58 | 3 | 72 | 1.0 | 1269.0 | 6533.6 | 1943.1 | 0.0 | -0.216 | 0.194 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC1806 | QL-IV-100 | 2 | 72 | 10.0 | 1269.0 | 18525.7 | 2822.7 | 1.0 | -0.255 | 0.069 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 10.0 | 1273.0 | 18525.7 | 2822.7 | 1.0 | -0.254 | 0.069 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 3.1623 | 1273.0 | 18525.7 | 2822.7 | 0.5 | -0.254 | 0.069 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | QL-V-73 | 3 | 72 | 10.0 | 1275.0 | 14413.7 | 2222.1 | 1.0 | -0.186 | 0.089 | 2.697 | HCC1806 QL-V-73 0 3 |
| HCC1806 | QL-XII-47 | 1 | 72 | 3.1623 | 1281.0 | 17793.8 | 2895.7 | 0.5 | -0.268 | 0.072 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC70 | Torin1 | 2 | 72 | 10.0 | 1286.0 | 7167.9 | 2409.0 | 1.0 | -0.329 | 0.179 | 1.573 | HCC70 Torin1 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 10.0 | 1288.0 | 18525.7 | 2822.7 | 1.0 | -0.251 | 0.070 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | QL-IV-100 | 1 | 72 | 10.0 | 1289.0 | 17793.8 | 2895.7 | 1.0 | -0.266 | 0.072 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | Torin2 | 2 | 72 | 3.1623 | 1297.0 | 18525.7 | 2822.7 | 0.5 | -0.249 | 0.070 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 10.0 | 1297.0 | 18525.7 | 2822.7 | 1.0 | -0.249 | 0.070 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC70 | QL-IV-100 | 3 | 72 | 1.0 | 1302.0 | 6533.6 | 1943.1 | 0.0 | -0.205 | 0.199 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 2 | 72 | 1.0 | 1333.0 | 7167.9 | 2409.0 | 0.0 | -0.314 | 0.186 | 1.573 | HCC70 QL-IV-100 0 2 |