Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | Torin2 | 1 | 72 | 3.1623 | 1160.0 | 17793.8 | 2895.7 | 0.5 | -0.295 | 0.065 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | QL-V-107 | 3 | 72 | 3.1623 | 1161.0 | 14413.7 | 2222.1 | 0.5 | -0.214 | 0.081 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC70 | Torin1 | 2 | 72 | 10.0 | 1162.0 | 7167.9 | 2409.0 | 1.0 | -0.371 | 0.162 | 1.573 | HCC70 Torin1 0 2 |
| HCC1806 | QL-IV-100 | 1 | 72 | 3.1623 | 1165.0 | 17793.8 | 2895.7 | 0.5 | -0.294 | 0.066 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | Torin2 | 2 | 72 | 1.0 | 1166.0 | 18525.7 | 2822.7 | 0.0 | -0.278 | 0.063 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | QL-IV-100 | 1 | 72 | 3.1623 | 1172.0 | 17793.8 | 2895.7 | 0.5 | -0.292 | 0.066 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 10.0 | 1175.0 | 17793.8 | 2895.7 | 1.0 | -0.291 | 0.066 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-73 | 3 | 72 | 10.0 | 1176.0 | 14413.7 | 2222.1 | 1.0 | -0.210 | 0.082 | 2.697 | HCC1806 QL-V-73 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 10.0 | 1178.0 | 6533.6 | 1943.1 | 1.0 | -0.249 | 0.180 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC1806 | Torin2 | 1 | 72 | 3.1623 | 1180.0 | 17793.8 | 2895.7 | 0.5 | -0.290 | 0.066 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 10.0 | 1190.0 | 17793.8 | 2895.7 | 1.0 | -0.288 | 0.067 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC70 | QL-X-138 | 3 | 72 | 10.0 | 1192.0 | 6533.6 | 1943.1 | 1.0 | -0.244 | 0.182 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC1806 | Torin2 | 1 | 72 | 1.0 | 1195.0 | 17793.8 | 2895.7 | 0.0 | -0.287 | 0.067 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | QL-IV-100 | 2 | 72 | 3.1623 | 1201.0 | 18525.7 | 2822.7 | 0.5 | -0.270 | 0.065 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 1.0 | 1201.0 | 7167.9 | 2409.0 | 0.0 | -0.358 | 0.168 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC1806 | Torin2 | 1 | 72 | 1.0 | 1201.0 | 17793.8 | 2895.7 | 0.0 | -0.285 | 0.068 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | QL-IV-100 | 2 | 72 | 10.0 | 1204.0 | 18525.7 | 2822.7 | 1.0 | -0.269 | 0.065 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 3 | 72 | 1.0 | 1205.0 | 6533.6 | 1943.1 | 0.0 | -0.239 | 0.184 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC1806 | Torin2 | 2 | 72 | 1.0 | 1207.0 | 18525.7 | 2822.7 | 0.0 | -0.269 | 0.065 | 2.714 | HCC1806 Torin2 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 1.0 | 1208.0 | 7167.9 | 2409.0 | 0.0 | -0.355 | 0.169 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 1.0 | 1211.0 | 18525.7 | 2822.7 | 0.0 | -0.268 | 0.065 | 2.714 | HCC1806 Torin2 0 2 |
| HCC70 | QL-X-138 | 3 | 72 | 10.0 | 1213.0 | 6533.6 | 1943.1 | 1.0 | -0.236 | 0.186 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 3.1623 | 1221.0 | 18525.7 | 2822.7 | 0.5 | -0.266 | 0.066 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 1.0 | 1224.0 | 7167.9 | 2409.0 | 0.0 | -0.350 | 0.171 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 3 | 72 | 1.0 | 1226.0 | 6533.6 | 1943.1 | 0.0 | -0.231 | 0.188 | 1.750 | HCC70 QL-VIII-58 0 3 |