Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-VI-86 | 3 | 72 | 10.0 | 1049.0 | 14413.7 | 2222.1 | 1.0 | -0.243 | 0.073 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 3.1623 | 1058.0 | 17793.8 | 2895.7 | 0.5 | -0.319 | 0.060 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | Torin2 | 1 | 72 | 1.0 | 1059.0 | 17793.8 | 2895.7 | 0.0 | -0.319 | 0.060 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | QL-XII-47 | 2 | 72 | 3.1623 | 1062.0 | 18525.7 | 2822.7 | 0.5 | -0.302 | 0.057 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC70 | QL-VI-86 | 1 | 72 | 3.1623 | 1062.0 | 7580.8 | 2503.8 | 0.5 | -0.415 | 0.140 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC1806 | QL-VI-86 | 3 | 72 | 10.0 | 1068.0 | 14413.7 | 2222.1 | 1.0 | -0.238 | 0.074 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC1806 | Torin2 | 2 | 72 | 1.0 | 1071.0 | 18525.7 | 2822.7 | 0.0 | -0.300 | 0.058 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 3.1623 | 1071.0 | 17793.8 | 2895.7 | 0.5 | -0.316 | 0.060 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 10.0 | 1071.0 | 17793.8 | 2895.7 | 1.0 | -0.316 | 0.060 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-VI-86 | 3 | 72 | 10.0 | 1071.0 | 14413.7 | 2222.1 | 1.0 | -0.237 | 0.074 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 3.1623 | 1074.0 | 18525.7 | 2822.7 | 0.5 | -0.300 | 0.058 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC70 | Torin2 | 1 | 72 | 0.3162 | 1092.0 | 7580.8 | 2503.8 | -0.5 | -0.405 | 0.144 | 1.598 | HCC70 Torin2 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 3.1623 | 1098.0 | 17793.8 | 2895.7 | 0.5 | -0.309 | 0.062 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-XII-47 | 2 | 72 | 3.1623 | 1099.0 | 18525.7 | 2822.7 | 0.5 | -0.294 | 0.059 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 10.0 | 1101.0 | 18525.7 | 2822.7 | 1.0 | -0.293 | 0.059 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | QL-V-73 | 3 | 72 | 10.0 | 1102.0 | 14413.7 | 2222.1 | 1.0 | -0.229 | 0.077 | 2.697 | HCC1806 QL-V-73 0 3 |
| HCC1806 | Torin2 | 1 | 72 | 1.0 | 1119.0 | 17793.8 | 2895.7 | 0.0 | -0.304 | 0.063 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 3.1623 | 1121.0 | 18525.7 | 2822.7 | 0.5 | -0.288 | 0.061 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | Torin2 | 1 | 72 | 3.1623 | 1125.0 | 17793.8 | 2895.7 | 0.5 | -0.303 | 0.063 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | QL-V-107 | 2 | 72 | 10.0 | 1130.0 | 18525.7 | 2822.7 | 1.0 | -0.286 | 0.061 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 10.0 | 1131.0 | 18525.7 | 2822.7 | 1.0 | -0.286 | 0.061 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 1.0 | 1136.0 | 7167.9 | 2409.0 | 0.0 | -0.380 | 0.158 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 3.1623 | 1139.0 | 18525.7 | 2822.7 | 0.5 | -0.284 | 0.062 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 3 | 72 | 1.0 | 1142.0 | 6533.6 | 1943.1 | 0.0 | -0.262 | 0.175 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 1.0 | 1153.0 | 6533.6 | 1943.1 | 0.0 | -0.258 | 0.176 | 1.750 | HCC70 QL-VIII-58 0 3 |