Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-VI-86 | 2 | 72 | 3.1623 | 870.0 | 7167.9 | 2409.0 | 0.5 | -0.477 | 0.121 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC1806 | QL-IV-100 | 3 | 72 | 10.0 | 871.0 | 14413.7 | 2222.1 | 1.0 | -0.293 | 0.060 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 3.1623 | 881.0 | 14413.7 | 2222.1 | 0.5 | -0.290 | 0.061 | 2.697 | HCC1806 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 0.3162 | 895.0 | 6533.6 | 1943.1 | -0.5 | -0.358 | 0.137 | 1.750 | HCC70 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 3.1623 | 899.0 | 14413.7 | 2222.1 | 0.5 | -0.285 | 0.062 | 2.697 | HCC1806 Torin2 0 3 |
| HCC70 | Torin2 | 1 | 72 | 0.3162 | 901.0 | 7580.8 | 2503.8 | -0.5 | -0.472 | 0.119 | 1.598 | HCC70 Torin2 0 1 |
| HCC1806 | Torin2 | 3 | 72 | 1.0 | 908.0 | 14413.7 | 2222.1 | 0.0 | -0.282 | 0.063 | 2.697 | HCC1806 Torin2 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 3.1623 | 917.0 | 6533.6 | 1943.1 | 0.5 | -0.349 | 0.140 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | Torin2 | 2 | 72 | 0.3162 | 925.0 | 7167.9 | 2409.0 | -0.5 | -0.456 | 0.129 | 1.573 | HCC70 Torin2 0 2 |
| HCC1806 | Torin2 | 3 | 72 | 1.0 | 926.0 | 14413.7 | 2222.1 | 0.0 | -0.277 | 0.064 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 3.1623 | 934.0 | 14413.7 | 2222.1 | 0.5 | -0.275 | 0.065 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC70 | Torin2 | 2 | 72 | 0.3162 | 942.0 | 7167.9 | 2409.0 | -0.5 | -0.449 | 0.131 | 1.573 | HCC70 Torin2 0 2 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 3.1623 | 950.0 | 17793.8 | 2895.7 | 0.5 | -0.347 | 0.053 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC70 | QL-VI-86 | 3 | 72 | 3.1623 | 960.0 | 6533.6 | 1943.1 | 0.5 | -0.332 | 0.147 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC1806 | QL-XII-47 | 2 | 72 | 3.1623 | 967.0 | 18525.7 | 2822.7 | 0.5 | -0.326 | 0.052 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-IV-100 | 3 | 72 | 10.0 | 975.0 | 14413.7 | 2222.1 | 1.0 | -0.263 | 0.068 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC70 | Torin2 | 3 | 72 | 0.3162 | 976.0 | 6533.6 | 1943.1 | -0.5 | -0.325 | 0.149 | 1.750 | HCC70 Torin2 0 3 |
| HCC1806 | QL-XII-47 | 2 | 72 | 3.1623 | 996.0 | 18525.7 | 2822.7 | 0.5 | -0.319 | 0.054 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC70 | Torin2 | 1 | 72 | 0.3162 | 1002.0 | 7580.8 | 2503.8 | -0.5 | -0.436 | 0.132 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 3.1623 | 1011.0 | 7580.8 | 2503.8 | 0.5 | -0.433 | 0.133 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 3.1623 | 1012.0 | 7580.8 | 2503.8 | 0.5 | -0.433 | 0.133 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 3.1623 | 1014.0 | 7580.8 | 2503.8 | 0.5 | -0.432 | 0.134 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 10.0 | 1018.0 | 17793.8 | 2895.7 | 1.0 | -0.329 | 0.057 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC70 | QL-IV-100 | 3 | 72 | 1.0 | 1027.0 | 6533.6 | 1943.1 | 0.0 | -0.305 | 0.157 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC1806 | QL-V-107 | 1 | 72 | 10.0 | 1047.0 | 17793.8 | 2895.7 | 1.0 | -0.322 | 0.059 | 2.619 | HCC1806 QL-V-107 0 1 |