Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | Torin2 | 2 | 72 | 0.001 | 5960.0 | 7167.9 | 2409.0 | -3.0 | 0.779 | 0.831 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.0032 | 5346.0 | 7167.9 | 2409.0 | -2.49 | 0.660 | 0.746 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.0032 | 5558.0 | 7167.9 | 2409.0 | -2.49 | 0.701 | 0.775 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.0032 | 6063.0 | 7167.9 | 2409.0 | -2.49 | 0.798 | 0.846 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.01 | 4457.0 | 7167.9 | 2409.0 | -2.0 | 0.479 | 0.622 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 1 | 72 | 0.001 | 7244.0 | 7580.8 | 2503.8 | -3.0 | 0.944 | 0.956 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.001 | 6711.0 | 7580.8 | 2503.8 | -3.0 | 0.853 | 0.885 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.001 | 6435.0 | 7580.8 | 2503.8 | -3.0 | 0.805 | 0.849 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0032 | 6216.0 | 7580.8 | 2503.8 | -2.49 | 0.766 | 0.820 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0032 | 6137.0 | 7580.8 | 2503.8 | -2.49 | 0.752 | 0.810 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.01 | 5027.0 | 7580.8 | 2503.8 | -2.0 | 0.547 | 0.663 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.01 | 4789.0 | 7580.8 | 2503.8 | -2.0 | 0.500 | 0.632 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.01 | 5237.0 | 7580.8 | 2503.8 | -2.0 | 0.587 | 0.691 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0316 | 3993.0 | 7580.8 | 2503.8 | -1.5 | 0.339 | 0.527 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.1 | 2596.0 | 7580.8 | 2503.8 | -1.0 | 0.023 | 0.342 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.1 | 2576.0 | 7580.8 | 2503.8 | -1.0 | 0.018 | 0.340 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.1 | 2732.0 | 7580.8 | 2503.8 | -1.0 | 0.056 | 0.360 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.3162 | 1092.0 | 7580.8 | 2503.8 | -0.5 | -0.405 | 0.144 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.3162 | 1002.0 | 7580.8 | 2503.8 | -0.5 | -0.436 | 0.132 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 1.0 | 263.0 | 7580.8 | 2503.8 | 0.0 | -0.756 | 0.035 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 1.0 | 268.0 | 7580.8 | 2503.8 | 0.0 | -0.753 | 0.035 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 3.1623 | 52.0 | 7580.8 | 2503.8 | 0.5 | -0.911 | 0.007 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 10.0 | 44.0 | 7580.8 | 2503.8 | 1.0 | -0.920 | 0.006 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 2 | 72 | 0.0316 | 3534.0 | 7167.9 | 2409.0 | -1.5 | 0.276 | 0.493 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.0316 | 3416.0 | 7167.9 | 2409.0 | -1.5 | 0.249 | 0.477 | 1.573 | HCC70 Torin2 0 2 |