Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
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HCC1806 | Torin1 | 2 | 72 | 0.001 | 17677.0 | 18525.7 | 2822.7 | -3.0 | 0.966 | 0.954 | 2.714 | HCC1806 Torin1 0 2 |
HCC70 | Torin1 | 1 | 72 | 3.1623 | 2686.0 | 7580.8 | 2503.8 | 0.5 | 0.045 | 0.354 | 1.598 | HCC70 Torin1 0 1 |
HCC70 | Torin1 | 1 | 72 | 10.0 | 1960.0 | 7580.8 | 2503.8 | 1.0 | -0.142 | 0.259 | 1.598 | HCC70 Torin1 0 1 |
HCC1806 | Torin1 | 2 | 72 | 0.001 | 18903.0 | 18525.7 | 2822.7 | -3.0 | 1.010 | 1.020 | 2.714 | HCC1806 Torin1 0 2 |
HCC70 | Torin1 | 2 | 72 | 0.001 | 6203.0 | 7167.9 | 2409.0 | -3.0 | 0.824 | 0.865 | 1.573 | HCC70 Torin1 0 2 |
HCC70 | Torin1 | 1 | 72 | 10.0 | 1998.0 | 7580.8 | 2503.8 | 1.0 | -0.132 | 0.264 | 1.598 | HCC70 Torin1 0 1 |
HCC1806 | Torin1 | 2 | 72 | 0.001 | 17557.0 | 18525.7 | 2822.7 | -3.0 | 0.961 | 0.948 | 2.714 | HCC1806 Torin1 0 2 |
HCC1806 | Torin1 | 2 | 72 | 0.001 | 18344.0 | 18525.7 | 2822.7 | -3.0 | 0.993 | 0.990 | 2.714 | HCC1806 Torin1 0 2 |
HCC70 | Torin1 | 1 | 72 | 1.0 | 1772.0 | 7580.8 | 2503.8 | 0.0 | -0.195 | 0.234 | 1.598 | HCC70 Torin1 0 1 |
HCC70 | Torin1 | 1 | 72 | 3.1623 | 2863.0 | 7580.8 | 2503.8 | 0.5 | 0.088 | 0.378 | 1.598 | HCC70 Torin1 0 1 |
HCC1806 | Torin1 | 1 | 72 | 10.0 | 4516.0 | 17793.8 | 2895.7 | 1.0 | 0.185 | 0.254 | 2.619 | HCC1806 Torin1 0 1 |
HCC70 | Torin1 | 1 | 72 | 3.1623 | 2555.0 | 7580.8 | 2503.8 | 0.5 | 0.013 | 0.337 | 1.598 | HCC70 Torin1 0 1 |
HCC70 | Torin1 | 1 | 72 | 1.0 | 3401.0 | 7580.8 | 2503.8 | 0.0 | 0.211 | 0.449 | 1.598 | HCC70 Torin1 0 1 |
HCC1806 | Torin1 | 1 | 72 | 10.0 | 4465.0 | 17793.8 | 2895.7 | 1.0 | 0.180 | 0.251 | 2.619 | HCC1806 Torin1 0 1 |
HCC1806 | Torin1 | 1 | 72 | 10.0 | 4559.0 | 17793.8 | 2895.7 | 1.0 | 0.189 | 0.256 | 2.619 | HCC1806 Torin1 0 1 |
HCC1806 | Torin1 | 1 | 72 | 3.1623 | 5747.0 | 17793.8 | 2895.7 | 0.5 | 0.299 | 0.323 | 2.619 | HCC1806 Torin1 0 1 |
HCC70 | Torin1 | 1 | 72 | 1.0 | 2938.0 | 7580.8 | 2503.8 | 0.0 | 0.105 | 0.388 | 1.598 | HCC70 Torin1 0 1 |
HCC1806 | Torin1 | 1 | 72 | 3.1623 | 6769.0 | 17793.8 | 2895.7 | 0.5 | 0.383 | 0.380 | 2.619 | HCC1806 Torin1 0 1 |
HCC70 | Torin1 | 2 | 72 | 0.001 | 6552.0 | 7167.9 | 2409.0 | -3.0 | 0.889 | 0.914 | 1.573 | HCC70 Torin1 0 2 |
HCC70 | Torin1 | 1 | 72 | 3.1623 | 2663.0 | 7580.8 | 2503.8 | 0.5 | 0.039 | 0.351 | 1.598 | HCC70 Torin1 0 1 |
HCC1806 | Torin1 | 1 | 72 | 3.1623 | 6390.0 | 17793.8 | 2895.7 | 0.5 | 0.353 | 0.359 | 2.619 | HCC1806 Torin1 0 1 |
HCC1806 | Torin1 | 1 | 72 | 10.0 | 4292.0 | 17793.8 | 2895.7 | 1.0 | 0.162 | 0.241 | 2.619 | HCC1806 Torin1 0 1 |
HCC1806 | Torin1 | 2 | 72 | 0.0032 | 17594.0 | 18525.7 | 2822.7 | -2.49 | 0.962 | 0.950 | 2.714 | HCC1806 Torin1 0 2 |
HCC70 | Torin1 | 1 | 72 | 0.3162 | 3437.0 | 7580.8 | 2503.8 | -0.5 | 0.219 | 0.453 | 1.598 | HCC70 Torin1 0 1 |
HCC70 | Torin1 | 1 | 72 | 0.3162 | 3455.0 | 7580.8 | 2503.8 | -0.5 | 0.223 | 0.456 | 1.598 | HCC70 Torin1 0 1 |